Modeling of summation of individual twitches into unfused tetanus for various types of rat motor units

Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology
Rositsa T RaikovaPiotr Krutki

Abstract

Repeated stimulation of motor units (MUs) causes an increase of the force output that cannot be explained by linear summation of equal twitches evoked by the same stimulation pattern. To explain this phenomenon, an algorithm for reconstructing the individual twitches, that summate into an unfused tetanus is described in the paper. The algorithm is based on an analytical function for the twitch course modeling. The input parameters of this twitch model are lead time, contraction and half-relaxation times and maximal force. The measured individual twitches and unfused tetani at 10, 20, 30 and 40 Hz stimulation frequency of three rat motor units (slow, fast resistant to fatigue and fast fatigable) are processed. It is concluded that: (1) the analytical function describes precisely the course of individual twitches; (2) the summation of equal twitches does not follow the results from the experimentally measured unfused tetani, the differences depend on the type of the MU and are bigger for higher values of stimulation frequency and fusion index; (3) the reconstruction of individual twitches from experimental tetanic records can be successful if the tetanus is feebly fused (fusion index up to 0.7); (4) both the maximal forces and ti...Continue Reading

References

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Citations

Mar 27, 2010·Biological cybernetics·Emma WilsonPhilip L Newland
Feb 18, 2011·Biological cybernetics·Emma WilsonPhilip L Newland
Nov 24, 2011·Journal of Neuroscience Methods·Paul D Gamlin, Joel M Miller
Aug 4, 2015·Journal of Biomechanics·Hanna Drzymała-CelichowskaPiotr Krutki
Apr 1, 2009·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·S WatanabeH Oka
Apr 10, 2007·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·R RaikovaH Aladjov
Apr 20, 2007·Computers in Biology and Medicine·Rositsa RaikovaJan Celichowski
Nov 6, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Dongwook KwakChangsu Na
Jun 30, 2006·Journal of Biomechanics·Brian R MacintoshDilson E Rassier
Apr 29, 2015·Neurological Research·Payam DibajHeinz Steffens
Mar 10, 2018·European Journal of Applied Physiology·Ian C SmithWalter Herzog
Oct 3, 2020·BMC Sports Science, Medicine and Rehabilitation·Joanna RakoczyJan Celichowski
Nov 23, 2020·European Journal of Applied Physiology·Ian C SmithWalter Herzog
Oct 20, 2019·Computers in Biology and Medicine·Vincent CarriouDavid Guiraud

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