Modeling skull electrical properties

Annals of Biomedical Engineering
R Sadleir, A Argibay

Abstract

Accurate representations and measurements of skull electrical conductivity are essential in developing appropriate forward models for applications such as inverse EEG or Electrical Impedance Tomography of the head. Because of its layered structure, it is often assumed that skull is anisotropic, with an anisotropy ratio around 10. However, no detailed investigation of skull anisotropy has been performed. In this paper we investigate four-electrode measurements of conductivities and their relation to tissue anisotropy ratio (ratio of tangential to radial conductivity) in layered or anisotropic biological samples similar to bone. It is shown here that typical values for the thicknesses and radial conductivities of individual skull layers produce tissue with much smaller anisotropy ratios than 10. Moreover, we show that there are very significant differences between the field patterns formed in a three-layered isotropic structure plausible for bone, and those formed assuming that bone is homogeneous and anisotropic. We performed a measurement of conductivity using an electrode configuration sensitive to the distinction between three-layered and homogeneous anisotropic composition and found results consistent with the sample being t...Continue Reading

References

Jan 1, 1991·Acta Oto-laryngologica. Supplementum·M J Peters, Jan C de Munck
Nov 1, 1968·Anesthesia and Analgesia·S Rush, D A Driscoll
Jul 1, 1983·Electroencephalography and Clinical Neurophysiology·D Cohen, B N Cuffin
Jul 1, 1993·Electroencephalography and Clinical Neurophysiology·J P WikswoS J Williamson
Jan 1, 1993·IEEE Transactions on Bio-medical Engineering·B N Cuffin
Mar 1, 1997·Electroencephalography and Clinical Neurophysiology·B J RothS Sato
Sep 19, 1998·Electroencephalography and Clinical Neurophysiology·S P van den BroekM J Peters
Sep 1, 1999·Medical Engineering & Physics·J O OllikainenJ P Kaipio
Mar 18, 2000·IEEE Transactions on Bio-medical Engineering·S Kun, R Peura
Nov 10, 2000·Brain Topography·M AkhtariW W Sutherling
Nov 15, 2000·IEEE Transactions on Bio-medical Engineering·Thom OostendorpDick Stegeman
May 11, 2002·Brain Topography·M AkhtariW W Sutherling
Jun 20, 2003·IEEE Transactions on Bio-medical Engineering·Sónia I GonçalvesFernando Lopes da Silva
Aug 29, 2003·IEEE Transactions on Bio-medical Engineering·Sónia I GonçalvesF H Lopes da Silva
Jul 14, 2004·IEEE Transactions on Bio-medical Engineering·J Malmivuo, Veikko E Suihko
Feb 10, 2006·Biomedical Engineering Online·Ceon RamonJ Haueisen
Apr 29, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·R N HoldeferM J Russell
Sep 1, 2006·IEEE Transactions on Bio-medical Engineering·Daniel GüllmarJürgen R Reichenbach
Oct 25, 2006·Biomedical Engineering Online·Ceon RamonPaul H Schimpf

Citations

Sep 18, 2009·Annals of Biomedical Engineering·R SadleirAaron Tucker
Jan 29, 2013·Brain Topography·Zeynep Akalin Acar, Scott Makeig
May 27, 2010·Australasian Physical & Engineering Sciences in Medicine·M R BasharP Wen
Sep 3, 2010·Australasian Physical & Engineering Sciences in Medicine·M R BasharP Wen
Nov 21, 2013·Annals of Biomedical Engineering·Yu DaiJianxun Zhang
Sep 5, 2013·Brain Topography·Victoria Montes-RestrepoHans Hallez
Jun 6, 2013·Computational and Mathematical Methods in Medicine·Zi Jun MengEung Je Woo
Feb 2, 2015·NeuroImage·Jae-Hyun ChoThomas R Knösche
Aug 26, 2015·NeuroImage·Zeynep Akalin AcarScott Makeig
Aug 7, 2010·Human Brain Mapping·M DannhauerThomas R Knösche
Sep 6, 2012·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Giulio RuffiniPedro Cavaleiro Miranda
Jul 24, 2014·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Zhi-De DengAngel V Peterchev
Nov 17, 2011·IEEE Transactions on Bio-medical Engineering·Tommaso De MarcoRoberto Guerrieri
Jun 28, 2014·NeuroImage·Johannes VorwerkCarsten H Wolters
May 16, 2012·NeuroImage·Benjamin LanferCarsten H Wolters
Apr 30, 2008·Physics in Medicine and Biology·Anuj J KapadiaCalvin R Howell
Apr 19, 2008·Physics in Medicine and Biology·Carey E FloydCalvin R Howell
Oct 22, 2009·Physiological Measurement·Chi TangXiuzhen Dong
Jan 15, 2020·Physics in Medicine and Biology·Joemini PoudelMark A Anastasio
Jul 12, 2011·Physiological Measurement·Shilpa PantR Sadleir
Mar 4, 2021·Journal of Neural Engineering·Mats ForssellPulkit Grover

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.