Modeling SSFP functional MRI contrast in the brain

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Karla L Miller, Peter Jezzard

Abstract

Steady-state free precession (SSFP) has recently been proposed for function MRI because of the potential for reducing image distortion and signal dropout. Several different contrast mechanisms have been suggested to explain the reported observations, but there has been limited work comparing theory with experiment in the brain. Moreover, the detailed work that has considered oxygen-dependent signal in SSFP outside the brain has focused on R(2) effects in the pass band, and largely neglected the signal contrast that occurs due to off-resonance effects. The article describes a model for SSFP functional contrast based on the convolution of the theoretical SSFP profile with the underlying frequency distribution. It is demonstrated that such a model must account for the effects of diffusion, which can alter the apparent R(2) and linespread. Monte Carlo simulations are used to calibrate corrections for these terms. This new model has the computational efficiency of the convolution model while encapsulating information from more time-consuming Monte Carlo simulations. This corrected convolution model is shown to agree well with experimental data, and model predictions and limitations are discussed.

References

Apr 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S OgawaP Glynn
Jul 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J L BoxermanR M Weisskoff
Dec 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·D A Yablonskiy, E M Haacke
Jun 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R M WeisskoffB R Rosen
Jun 11, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R B BuxtonL R Frank
Apr 16, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·V G Kiselev, S Posse
May 8, 1999·Journal of Magnetic Resonance Imaging : JMRI·J P WansapuraW S Ball
Jan 24, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Klaus Scheffler, Jürgen Hennig
Oct 3, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Karla L MillerJohn M Pauly
Oct 27, 2004·NeuroImage·Stephen M SmithPaul M Matthews
Feb 22, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Rohan DharmakumarGraham A Wright
Dec 14, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Karla L MillerJohn M Pauly
May 9, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Rohan DharmakumarGraham A Wright
Jul 11, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Carl Ganter
Dec 28, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kai ZhongOliver Speck
Feb 29, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jain Mangalathu ArumanaRohan Dharmakumar

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Citations

Mar 28, 2012·Proceedings of the National Academy of Sciences of the United States of America·Sébastien SerresNicola R Sibson
Mar 13, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Hao SunJon-Fredrik Nielsen
Mar 1, 2012·International Journal of Imaging Systems and Technology·Taek Soo KimJohn M Pauly
May 24, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Eric R Muir, Timothy Q Duong
Apr 8, 2010·Journal of Magnetic Resonance Imaging : JMRI·Xiangzhi ZhouRohan Dharmakumar
Oct 16, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Hao SunJon-Fredrik Nielsen
Jan 26, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Karla L Miller
Jan 26, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Xiangzhi ZhouRohan Dharmakumar
Aug 25, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Klaus Scheffler, Philipp Ehses
Dec 18, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jun HuaCraig K Jones
Jun 4, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Tiffany JouChris V Bowen
May 23, 2015·Frontiers in Neuroscience·Valentin G KemperEssa Yacoub
Nov 1, 2011·NeuroImage·Karla L Miller
May 27, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Philipp Ehses, Klaus Scheffler
May 23, 2015·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Sung-Hong ParkSeung Hong Choi
Jan 9, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Shouchang Guo, Douglas C Noll
Apr 15, 2020·Journal of Magnetic Resonance Imaging : JMRI·Jakob Assländer
Feb 11, 2020·Frontiers in Neuroinformatics·Francesca MandinoJoanes Grandjean
Nov 4, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Marlon Pérez-RodasRahel Heule
Nov 18, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Peter J LallyNeal K Bangerter
Aug 28, 2021·Scientific Reports·Gyula KotekJuan A Hernandez-Tamames

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