PMID: 9002863May 1, 1996Paper

Modeling the caries-inhibitory effects of dental materials

Dental Materials : Official Publication of the Academy of Dental Materials
J D Featherstone

Abstract

The objectives of this review are to compare the models that are used to simulate the caries process in cardiology research and to suggest how these models might be used to assess caries-inhibitory properties of dental materials. Available caries-simulation models fall into the following classifications: 1) in vitro demineralization using acid buffers, 2) in vitro demineralization using bacterially generated acids, 3) in vitro demineralization/remineralization using a pH-cycling system, 4) an artificial mouth where a bacterially generated acid challenge is interspersed with a "saliva" treatment, 5) in vivo animal model (generally with rats), 6) in situ demineralization and/or remineralization using enamel or dentin blocks or slices in the human mouth, and 7) in vivo studies using teeth scheduled for extraction in the human mouth. Most dental materials studies have used simple in vitro demineralization models or component release experiments, each of which is inadequate to answer the questions that are being asked about the caries-inhibitory properties of the material being tested. Experimental methods must be chosen with care to ensure that the material to be tested is examined in an appropriate mode. The ultimate goal is to co...Continue Reading

References

Jul 1, 1987·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·M M O'Reilly, J D Featherstone
Jan 1, 1981·Caries Research·J D Featherstone, J R Mellberg
Feb 1, 1993·Journal of Dental Research·D H LeverettR J Billings

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Citations

Feb 22, 2012·Lasers in Medical Science·Vinicius Rangel Geraldo-MartinsRegina Guenka Palma-Dibb
Apr 25, 2012·Environmental Monitoring and Assessment·Venkataramann SivasankarA Chandramohan
Aug 19, 2007·Journal of Materials Science. Materials in Medicine·Omar T Al-NaimiJohn F McCabe
Nov 27, 2002·Journal of Dentistry·Anderson Takeo HaraAntonio Luiz Rodrigues
Feb 12, 2009·Caries Research·L E BertassoniG W Marshall
Apr 1, 2003·European Journal of Oral Sciences·John F McCabeSharanbir K Sidhu
Jul 22, 1998·Community Dentistry and Oral Epidemiology·J A Weintraub
Jul 22, 1998·Community Dentistry and Oral Epidemiology·A I Ismail
Jul 11, 2000·International Dental Journal·E ReichE Newbrun
Oct 2, 2015·Dental Materials : Official Publication of the Academy of Dental Materials·Asbjørn Jokstad
Nov 17, 2007·Dental Materials : Official Publication of the Academy of Dental Materials·Marcelo M PintoHumberto N Yoshimura
Nov 17, 2007·Journal of Esthetic and Restorative Dentistry : Official Publication of the American Academy of Esthetic Dentistry ... [et Al.]·Flávia L B AmaralSilmara A M Corona
Feb 14, 2006·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Tahani A Al-MusallamChristine D Wu
Sep 20, 2005·International Dental Journal·P ThaveesangpanichJ S Wefel
Nov 10, 2010·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Vuk Uskoković, Dragan P Uskoković
Jul 15, 2015·BMC Oral Health·Tathiane Larissa LenziDaniela Prócida Raggio
Dec 24, 2010·Archives of Oral Biology·M Esteves-OliveiraC P Eduardo
Mar 6, 2015·Journal of Oral Microbiology·Krista M Salli, Arthur C Ouwehand
Feb 1, 1997·Community Dentistry and Oral Epidemiology·N B Pitts
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Oct 19, 2005·Brazilian Oral Research·Rosa Helena Miranda GrandePaulo Christino Neto
Jun 27, 2006·Journal of Dental Research·A T HaraD T Zero
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Mar 2, 2006·Caries Research·J M ten CateM J Buijs
Oct 31, 2001·Public Health Nutrition·A Sheiham
May 20, 2020·Photobiomodulation, Photomedicine, and Laser Surgery·Nur Burcu UlusoyZafer Cavit Cehreli
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Oct 2, 2015·The Journal of Contemporary Dental Practice·Tathiane Larissa LenziRachel de Oliveira Rocha

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