Modeling the impact of comorbidity on breast cancer patient outcomes.

Health Care Management Science
Shengfan ZhangKathleen M Diehl

Abstract

The objective of this paper is to model the impact of comorbidity on breast cancer patient outcomes (e.g., length of stay and disposition). Previous studies suggest that comorbidities may significantly affect mortality risks for breast cancer patients. The 2006 AHRQ Nationwide Inpatient Sample (NIS) is used to analyze the relationships among comorbidities (e.g., hypertension, diabetes, obesity, and mental disorder), total charges, length of stay, and patient disposition as a function of age and race. A multifaceted approach is used to quantify these relationships. A causal study is performed to explore the effect of various comorbidities on patient outcomes. Least squares regression models are developed to evaluate and compare significant factors that influence total charges and length of stay. Logistic regression is used to study the factors that may cause patient mortality or transferring. In addition, different survival models are developed to study the impact of comorbidity on length of stay with censoring information. This study shows the interactions and relationship among various comorbidities and breast cancer. It shows that certain hypertension may not increase length of stay and total charges; diabetes behaves differe...Continue Reading

References

Feb 7, 1998·Medical Care·A ElixhauserR M Coffey
Oct 1, 1998·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·C J NewschafferM Diener-West
May 13, 1999·Clinical Therapeutics·S Z ZhaoL M Arguelles
Mar 17, 2001·JAMA : the Journal of the American Medical Association·R YancikJ W Yates
May 3, 2003·Journal of Clinical Epidemiology·Vincent de GrootLex M Bouter
Aug 20, 2003·CA: a Cancer Journal for Clinicians·Chris E Holmes, Hyman B Muss
Dec 9, 2003·The Breast : Official Journal of the European Society of Mastology·Pekka J KlemiHans Helenius
Mar 27, 2004·Annals of Family Medicine·Barbara StarfieldJonathan P Weiner
May 27, 2004·JAMA : the Journal of the American Medical Association·Jay F PiccirilloEdward L Spitznagel
Jul 10, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·C SouvignetL Baril
Jan 15, 2005·Health Care Management Science·Sakesun Suthummanon, Vincent K Omachonu
Oct 7, 2005·Arthritis and Rheumatism·Kelli L DominickHayden B Bosworth
Oct 13, 2005·JAMA : the Journal of the American Medical Association·C Martin TammemagiDavid Nathanson
Oct 7, 2006·Journal of the Society for Integrative Oncology·John A AstinUNKNOWN Susan G. Komen Breast Cancer Foundation
Nov 23, 2006·Archives of Surgery·Edward H Livingston, Joshua Langert
Jan 24, 2007·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
Jun 6, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Timothy L LashRebecca A Silliman
Feb 23, 2008·The Annals of Thoracic Surgery·Robert A MeguidStephen C Yang
Jan 10, 2009·International Journal of Surgery·Francesca RoveraRenzo Dionigi
Mar 3, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Ann AlbrightDesmond E Williams
Feb 26, 2009·Health Affairs·Charles RoehrigJenny Bryant
Sep 22, 2009·Breast Cancer Research and Treatment·Vijayakrishna K Gadi
Oct 31, 2009·The Journal of Pediatrics·Sarah E Barlow
Nov 27, 2009·Health Care Management Science·Margaret L Brandeau, Gregory S Zaric

❮ Previous
Next ❯

Citations

Apr 20, 2010·Annals of Surgical Oncology·Kathleen Diehl, Lisa A Newman
Jan 20, 2012·Critical Reviews in Oncology/hematology·Paolo CarliDiana Crivellari
Aug 2, 2015·Cancer Epidemiology·Tomi F AkinyemijuHenna Budhwani
Jun 4, 2015·PloS One·Neomi Vin-RavivDana H Bovbjerg
Feb 1, 2018·BMC Health Services Research·Jan WolffKlaus Kaier
Jun 6, 2018·Expert Review of Pharmacoeconomics & Outcomes Research·Jaya S KhushalaniDonatus U Ekwueme

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Critical Reviews in Oncology/hematology
Wilson Gonsalves, Apar Kishor Ganti
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Karen W L YeeLillian L Siu
© 2021 Meta ULC. All rights reserved