Nov 10, 2015

Modeling Transitions between Responsive and Resistant States in Breast Cancer with Application to Therapy Optimization

BioRxiv : the Preprint Server for Biology
Chun ChenWilliam Baumann

Abstract

We present a mathematical model that captures the transitions among three experimentally observed estrogen sensitivity phenotypes in breast cancer cells. Based on this model, a population-level model is created and used to explore the optimization of a therapeutic protocol

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Mentioned in this Paper

Treatment Protocols
Population Group
Estrogens
Breast Carcinoma
Malignant Neoplasm of Breast
Estrogen [EPC]
Estrogen Measurement
Breast Cancer Cell

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