Jan 19, 2012

Modeling two-photon calcium fluorescence of episodic V1 recordings using multifrequency analysis

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Henry W ZhengEmery N Brown


The use of two-photon microscopy allows for imaging of deep neural tissue in vivo. This paper examines frequency-based analysis to two-photon calcium fluorescence images with the goal of deriving smooth tuning curves. We present a multifrequency analysis approach for improved extraction of calcium responses in episodic stimulation experiments, that is, when the stimulus is applied for a number of frames, then turned off for the next few frames, and so on. Episodic orientation stimulus was applied while recording from the primary visual cortex of an anesthetized mouse. The multifrequency model demonstrated improved tuning curve descriptions of the neurons. It also offers perspective regarding the characteristics of calcium fluorescence imaging of the brain.

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Calcium [EPC]
Brodmann Area 17
Area Striata Structure
Calcium Supplements
Calcium Measurement

Related Feeds

BRAIN Initiative Cell Census Network (BICCN)

The BRAIN Initiative Cell Census Network aims to identify and provide experimental access to the different brain cell types to determine their roles in health and disease. Discover the latest research from researchers in the BRAIN Initiative Cell Census Network here.

Brain-Computer Interface

A brain-computer interface, also known as a brain-machine interface, is a bi-directional communication pathway between an external device and a wired brain. Here is the latest research on this topic.

Related Papers

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
S Müller
Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Juliana YordanovaVasil Kolev
IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society
Stelios Krinidis, Vassilios Chatzis
© 2020 Meta ULC. All rights reserved