Modelling childhood caries using parametric competing risks survival analysis methods for clustered data

Caries Research
J StephensonE T Treasure

Abstract

Caries in primary teeth is an ongoing issue in children's dental health. Its quantification is affected by clustering of data within children and the concurrent risk of exfoliation of primary teeth. This analysis of caries data of 103,776 primary molar tooth surfaces from a cohort study of 2,654 British children aged 4-5 years at baseline applied multilevel competing risks survival analysis methodology to identify factors significantly associated with caries occurrence in primary tooth surfaces in the presence of the concurrent risk of exfoliation, and assessed the effect of exfoliation on caries development. Multivariate multilevel parametric survival models were applied at surface level to the analysis of the sound-carious and sound-exfoliation transitions to which primary tooth surfaces are subject. Socio-economic class, fluoridation status and surface type were found to be the strongest predictors of primary caries, with the highest rates of occurrence and lowest median survival times associated with occlusal surfaces of children from poor socio-economic class living in non-fluoridated areas. The concurrent risk of exfoliation was shown to reduce the distinction in survival experience between different types of surfaces, an...Continue Reading

Citations

Apr 4, 2013·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·T KäkilehtoV Anttonen
Apr 9, 2010·Diabetology & Metabolic Syndrome·Roya KelishadiParinaz Poursafa
Mar 5, 2016·Clinical Implant Dentistry and Related Research·Xixi WuFaleh Tamimi
Mar 7, 2012·Community Dentistry and Oral Epidemiology·Paul BrocklehurstMartin Tickle
Jul 2, 2011·International Journal of Paediatric Dentistry·Boniek C D BorgesIsauremi V De Assunção Pinheiro
Jan 4, 2012·International Journal of Paediatric Dentistry·Vuokko AnttonenLeo Tjäderhane
Nov 18, 2014·Community Dentistry and Oral Epidemiology·Hyo-Jin LeeKwang-Hak Bae
Mar 6, 2013·Journal of Dentistry·Ailish Hannigan, Christopher D Lynch
Jul 25, 2014·Journal of Dental Research·J P NeyD L Chi
Sep 22, 2018·Journal of Public Health Dentistry·Tariq S GhazalJustine L Kolker

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