Modelling insights into the COVID-19 pandemic

Paediatric Respiratory Reviews
Michael T MeehanEmma S McBryde

Abstract

Coronavirus disease 2019 (COVID-19) is a newly emerged infectious disease caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that was declared a pandemic by the World Health Organization on 11th March, 2020. Response to this ongoing pandemic requires extensive collaboration across the scientific community in an attempt to contain its impact and limit further transmission. Mathematical modelling has been at the forefront of these response efforts by: (1) providing initial estimates of the SARS-CoV-2 reproduction rate, R0 (of approximately 2-3); (2) updating these estimates following the implementation of various interventions (with significantly reduced, often sub-critical, transmission rates); (3) assessing the potential for global spread before significant case numbers had been reported internationally; and (4) quantifying the expected disease severity and burden of COVID-19, indicating that the likely true infection rate is often orders of magnitude greater than estimates based on confirmed case counts alone. In this review, we highlight the critical role played by mathematical modelling to understand COVID-19 thus far, the challenges posed by data availability and uncertainty, and the continuing utili...Continue Reading

Citations

Dec 10, 2020·The Medical Journal of Australia·James M TrauerEmma S McBryde
Mar 7, 2021·International Journal of Environmental Research and Public Health·Eunha Shim
Apr 6, 2021·Journal of Empirical Research on Human Research Ethics : JERHRE·Evgenia Muginshtein-SimkovitchNoam Fink
May 25, 2021·Zeitschrift für Gesundheitswissenschaften = Journal of public health·Bernd BrüggenjürgenStefan N Willich
Jun 16, 2021·Modeling Earth Systems and Environment·Shraddha Ramdas Bandekar, Mini Ghosh
Aug 8, 2021·International Journal of Environmental Research and Public Health·Simin Zou, Xuhui He
Aug 22, 2021·Paediatric Respiratory Reviews·Jamie M CaldwellEmma S McBryde
Aug 16, 2021·Computer Methods and Programs in Biomedicine·Regina PadmanabhanMohammed Abdulla Al-Hitmi
Sep 4, 2021·The Medical Journal of Australia·Emma S McBrydeRobert C Cope

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Emerging Microbes & Infections
Shabir Ahmad Lone, Aijaz Ahmad
Critical Care Nursing Quarterly
Osakpolor OgbeborNitin Bhanot
Journal of Radiology Nursing
Robert ElliottAshwani Kumar Sharma
© 2021 Meta ULC. All rights reserved