Modelling the PSI response in general anesthesia.

Journal of Clinical Monitoring and Computing
Gerardo Alfonso PérezAna María León Fragoso

Abstract

In anesthesia automation, one of the main important issues is the availability of a reliable measurement of the depth of consciousness level (hypnosis) of the patient. According to this value, the hypnotic drug dosage can be adequately calculated. One of the most studied hypnosis indexes is the bispectral index (BIS). In this article we analyzed an alternative called patient state index (PSI). The objectives of this study are, first, to validate the accuracy of the PSI describing the hypnosis level during the maintenance phase of general anesthesia, by comparing with the BIS and, second, to model the relationship between propofol infusion rate and PSI values, obtained from a SEDLine monitor. For this, real data from patients undergoing general anesthesia simultaneously monitored with both BIS and PSI signals was used. Results obtained are interesting for a correct interpretation of PSI signal in clinical practice.

References

Dec 16, 2003·Intensive Care Medicine·Gerhard SchneiderEberhard F Kochs
Jan 27, 2004·British Journal of Anaesthesia·L S PrichepW J Kox
Oct 13, 2009·Anesthesia and Analgesia·Junxia TangRoderic G Eckenhoff
Jul 9, 2010·Anesthesiology·Agnes RigouzzoIsabelle Constant
Oct 3, 2012·Journal of Neurosurgical Anesthesiology·Matthew T V ChanUNKNOWN CODA Trial Group
Sep 3, 2013·Anaesthesia·I Martín-MateosA León
Oct 16, 2014·Surgical Neurology International·Saeed MahmoodRifat Latifi
Jun 14, 2016·Computers in Biology and Medicine·I Martín-MateosJ F Gómez-González
Sep 21, 2016·Computer Methods and Programs in Biomedicine·Filipa N NogueiraP Rocha
Jul 19, 2018·Clinical Pharmacokinetics·Marko M SahinovicAnthony R Absalom
Nov 6, 2018·Minerva anestesiologica·José A RebosoJuan A Mendez-Perez

❮ Previous
Next ❯

Citations

Oct 30, 2021·Journal of Clinical Monitoring and Computing·Teiji SawaYurie Obata

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.