Modelling the UNAIDS 90-90-90 treatment cascade for gay, bisexual and other men who have sex with men in South Africa: using the findings of a data triangulation process to map a way forward

AIDS and Behavior
Andrew ScheibeHelen Struthers

Abstract

A data triangulation exercise was carried out between 2013 and 2015 to assess the HIV epidemic and response among gay, bisexual and other men who have sex with men (GBMSM) in South Africa. We used the findings to assess progress in achieving the UNAIDS 90-90-90 goals for GBMSM in the country. Three scenarios were developed using different GBMSM population factors (2.0, 3.5 and 5.0% of males aged ≥15) to estimate the population size, HIV prevalence of 13.2-49.5%, and 68% of GBMSM knowing their status. Due to data gaps, general population data were used as estimates of GBMSM on antiretroviral therapy (ART) and virologically suppressed (25.7 and 84.0%, respectively). The biggest gap is access to ART. To address the data gap we recommend developing data collection tools, indicators, and further quantification of HIV cascades. Targeted testing, linkage to services and scaled-up prevention interventions (including pre-exposure prophylaxis) are also required.

References

Aug 3, 1999·American Journal of Epidemiology·E VittinghoffS P Buchbinder
Jun 16, 2009·Reproductive Health Matters·Laetitia C Rispel, Carol A Metcalf
Jul 21, 2009·Lancet·Adrian D SmithHarold W Jaffe
Feb 8, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Laetitia Charmaine RispelCarl Lombard
Dec 17, 2011·International Journal of STD & AIDS·J KnoxS Maimane
Jan 24, 2012·Current HIV Research·Denis M TebitMiguel E Quiñones-Mateu
Jul 24, 2012·Lancet·Chris BeyrerRon Brookmeyer
Oct 2, 2015·The Lancet. HIV·Morna CornellUNKNOWN International Epidemiologic Databases to Evaluate AIDS-Southern Africa Collaboration

❮ Previous
Next ❯

Citations

Nov 30, 2019·African Journal of AIDS Research : AJAR·Catherine Barker CantelmoArin Dutta
Jul 5, 2019·Expert Review of Vaccines·Jean-Louis Excler, Jerome H Kim
Jul 24, 2018·Journal of the International AIDS Society·Avi Joseph HakimJesus Maria Garcia Calleja

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The New England Journal of Medicine
Michael C ThigpenLynn A Paxton
The New England Journal of Medicine
Chris Kenyon, Robert Colebunders
The New England Journal of Medicine
Mark J Bolland, Andrew Grey
The New England Journal of Medicine
Lut Van Damme, Amy Corneli
The New England Journal of Medicine
Jared M Baeten, Connie Celum
© 2021 Meta ULC. All rights reserved