Jan 18, 2018

Moderators of Treatment Outcomes After Telehealth Self-Management and Education in Adults With Multiple Sclerosis: A Secondary Analysis of a Randomized Controlled Trial

Archives of Physical Medicine and Rehabilitation
Dawn M EhdeAaron P Turner


To examine moderators of treatment effects in a randomized controlled trial comparing a telehealth self-management intervention with a telehealth multiple sclerosis (MS) education intervention for fatigue, pain, and mood in adults with MS. Secondary analysis of a single-blind randomized controlled trial. Community. Adults with MS and chronic fatigue, chronic pain, and/or moderate depressive symptoms (N=163) recruited from across the United States. Two 8-week, telephone-delivered symptom interventions delivered 1:1: a self-management intervention (n=75) and an MS education intervention (n=88). Outcome measures were fatigue impact pain interference, and depressive symptom severity assessed at baseline and posttreatment. Potential moderators of treatment effects assessed at baseline were demographics (age, sex, and education), clinical characteristics (disease duration and disability severity), symptoms (perceived cognitive impairment and pain intensity), baseline levels of the treatment outcomes (pain interference, fatigue impact and depressive symptom severity), and cognitive behavioral factors (pain catastrophizing, fatigue catastrophizing, self-efficacy, and patient activation). Moderation analyses found significant moderation...Continue Reading

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Mentioned in this Paper

Widespread Chronic Pain
Randomized Controlled Trial (Publication)
Mass Spectrometry
Controlled Clinical Trials, Randomized
Blinded Clinical Study
Clinical Aspects
Depressive Symptoms
Chronic Pain

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