Modern clinical management helps reducing the impact of type 1 diabetes in children

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Andrea E Scaramuzza, Gian Vincenzo Zuccotti

Abstract

Type 1 diabetes care may be very costly not only in terms of money but also in terms of psychological and therapeutic acceptance and compliance. Recently, a lot of new technologies have been introduced in the care of patients with type 1 diabetes that should allow them to achieve an improvement in glycemic control, quality of life and above all prevent long-term complications. Combining continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusion (CSII) provides a more useful tool for patients with type 1 diabetes, the sensor-augmented pump (SAP). The aim of the present review is to explore SAP efficacy and safety in young patients with type 1 diabetes. SAP demonstrated increased efficacy in lowering glycated hemoglobin when compared either to multiple daily injections or CSII alone. Its efficacy is positively associated with CGM use, baseline HbA1c and patients' age. According to currently available evidence, SAP seems sufficiently safe, effective and beneficial in improving glycemic control in pediatric patients with type 1 diabetes. Moreover, encouraging results using semi-closed loop systems are emerging, paving the way toward a fully automated artificial pancreas. As pediatric diabetologists we have the...Continue Reading

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Citations

Apr 18, 2015·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Moufida Ben Nasr, Paolo Fiorina
Jul 9, 2016·Pediatric Diabetes·Kevin KaisermanMyriam Rosilio

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