Modern management of the cancer anorexia-cachexia syndrome

Current Pain and Headache Reports
K A Nelson

Abstract

The cancer anorexia-cachexia syndrome is common, occurring in 80% of patients with advanced-stage cancer, and it is one of the most frequent causes of death in patients with cancer. It is a complex problem involving abnormalities in protein, carbohydrate, and fat metabolism. Tumors have both direct and indirect effects that result in anorexia and weight loss. The disease burden does not necessarily correlate with the degree of cachexia. In addition to the physical manifestations, the resulting abnormalities have a significant psychologic effect on patients and their families. Although there is no treatment to reverse the process, pharmacologic and nonpharmacologic measures can enhance food intake and improve quality of life.

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Citations

Aug 26, 2009·International Journal of Clinical Oncology·Masanori TakahashiGo Wakabayashi
Oct 16, 2003·Nutrition·David R Thomas
Feb 19, 2002·Journal of the American College of Surgeons·Alexandra M EassonDennis L Johnson
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Aug 31, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·John M KirkwoodLori Stover
Feb 27, 2003·The Oncologist·Francois G el-KamarPeter S Kozuch

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