Modern statistical modeling approaches for analyzing repeated-measures data

Nursing Research
Matthew J Hayat, Haley Hedlin

Abstract

Researchers often describe the collection of repeated measurements on each individual in a study design. Advanced statistical methods, namely, mixed and marginal models, are the preferred analytic choices for analyzing this type of data. The aim was to provide a conceptual understanding of these modeling techniques. An understanding of mixed models and marginal models is provided via a thorough exploration of the methods that have been used historically in the biomedical literature to summarize and make inferences about this type of data. The limitations are discussed, as is work done on expanding the classic linear regression model to account for repeated measurements taken on an individual, leading to the broader mixed-model framework. A description is provided of a variety of common types of study designs and data structures that can be analyzed using a mixed model and a marginal model. This work provides an overview of advanced statistical modeling techniques used for analyzing the many types of correlated .data collected in a research study.

References

Jul 1, 1995·Nursing·P Angelucci
Nov 10, 2001·BMJ : British Medical Journal·A J Vickers, D G Altman
Apr 3, 2002·Journal of Clinical Epidemiology·Jos Twisk, Wieke de Vente
Jul 16, 2002·Journal of Epidemiology and Community Health·A V Diez Roux
Feb 8, 2003·Twin Research : the Official Journal of the International Society for Twin Studies·Shaun Purcell
Nov 5, 2003·Nursing·Michael W Day
Mar 12, 2004·Nursing Outlook·Nancy DuntonJan Moore
Jul 16, 2005·Journal of Epidemiology and Community Health·Jos W R TwiskWieke de Vente
Nov 5, 2008·Circulation·Garrett M Fitzmaurice, Caitlin Ravichandran
Dec 11, 2008·Prevention Science : the Official Journal of the Society for Prevention Research·Deborah GrossHartmut Mokros
May 7, 2010·Nursing Research·Matthew J Hayat
Jul 22, 2010·Nursing·Katharine M Scarbrough
Dec 15, 2011·Nursing Research·Lynn Y Unruh, Ning Jackie Zhang
Feb 22, 2012·Nursing·Darla Banks, Kimberley Trull
Apr 1, 2001·Multivariate Behavioral Research·D LivertM Stirratt

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Citations

Feb 3, 2016·Journal of Nursing Management·Taina PitkäahoKatri Vehviläinen-Julkunen
Mar 25, 2014·The Journal of Nursing Education·Matthew J Hayat, Melinda Higgins
Jul 19, 2016·Journal of Forensic Nursing·Erin N PollittDaniel J Sheridan
Jul 21, 2017·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Richard A Armstrong
Jun 16, 2018·Research in Nursing & Health·Dawn M AycockPatricia C Clark

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