Modifiable risk factors predicting major depressive disorder at four year follow-up: a decision tree approach.

BMC Psychiatry
Philip J BatterhamA J Mackinnon

Abstract

Relative to physical health conditions such as cardiovascular disease, little is known about risk factors that predict the prevalence of depression. The present study investigates the expected effects of a reduction of these risks over time, using the decision tree method favoured in assessing cardiovascular disease risk. The PATH through Life cohort was used for the study, comprising 2,105 20-24 year olds, 2,323 40-44 year olds and 2,177 60-64 year olds sampled from the community in the Canberra region, Australia. A decision tree methodology was used to predict the presence of major depressive disorder after four years of follow-up. The decision tree was compared with a logistic regression analysis using ROC curves. The decision tree was found to distinguish and delineate a wide range of risk profiles. Previous depressive symptoms were most highly predictive of depression after four years, however, modifiable risk factors such as substance use and employment status played significant roles in assessing the risk of depression. The decision tree was found to have better sensitivity and specificity than a logistic regression using identical predictors. The decision tree method was useful in assessing the risk of major depressive ...Continue Reading

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Citations

Dec 2, 2010·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Michel Lejoyeux, Philippe Lehert
Feb 26, 2011·International Journal of Epidemiology·Kaarin J AnsteyAnthony F Jorm
Sep 6, 2011·The Australian and New Zealand Journal of Psychiatry·Seetal DoddMichael Berk
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Apr 28, 2012·The British Journal of Psychiatry : the Journal of Mental Science·Kathleen MulliganNeil Greenberg
Jul 31, 2012·Journal of Affective Disorders·Philip J Batterham, Helen Christensen
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Aug 9, 2016·Journal of Behavioral Addictions·Mi Jung RhoDai-Jin Kim
Apr 14, 2016·Maternal and Child Health Journal·Leónides FernándezMaría Marín
Nov 20, 2020·Neuropsychiatric Disease and Treatment·Mengxue Zhao, Zhengzhi Feng
Aug 14, 2020·Physiological Reviews·Eus J W Van Someren

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