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Modification of arginine and lysine in proteins with 2,4-pentanedione

Biochemistry

Nov 18, 1975

H F Gilbert, M H O'Leary

Abstract

Primary amines react with 2,4-pentanedione at pH 6-9 to form enamines, N-alkyl-4-amino-3-penten-2-ones. The latter compounds readily regenerate the primary amine at low pH or on treatment with hydroxylamine. Guanidine and substituted guanidines react with 2,4-pentanedione to form N-subs...read more

Mentioned in this Paper

LYZ gene
Hydrogen-Ion Concentration
Urine Lysine Measurement
Amines
Ketones
Leftose
Lysine
Enzyme Activity
Micrococcus
Amine Group
64
Paper Details
References
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  • Citations24
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Modification of arginine and lysine in proteins with 2,4-pentanedione

Biochemistry

Nov 18, 1975

H F Gilbert, M H O'Leary

PMID: 43

DOI: 10.1021/bi00694a027

Abstract

Primary amines react with 2,4-pentanedione at pH 6-9 to form enamines, N-alkyl-4-amino-3-penten-2-ones. The latter compounds readily regenerate the primary amine at low pH or on treatment with hydroxylamine. Guanidine and substituted guanidines react with 2,4-pentanedione to form N-subs...read more

Mentioned in this Paper

LYZ gene
Hydrogen-Ion Concentration
Urine Lysine Measurement
Amines
Ketones
Leftose
Lysine
Enzyme Activity
Micrococcus
Amine Group
64
Paper Details
References
  • References
  • Citations24
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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