PMID: 6821578Jan 1, 1980Paper

Modification of mouse immune responses against allogeneic tumor by pretreatment of antigen with mitomycin C or X-irradiation

Journal of Immunopharmacology
C C HoffmannE Mihich

Abstract

Treatment of P815 mastocytoma cells with mitomycin C or X-irradiation prior to their inoculation into an allogeneic host resulted in a shift in the appearance of the peak of the T-killer cell population from day 10 to day 6. This finding is discussed in relation to the caution that must be exerted in extrapolating data obtained in studies in vitro using one-way mixed lymphocyte cultures to in vivo model systems involving proliferating tumor cells as immunogens.

Citations

Jan 1, 1983·International Journal of Immunopharmacology·M J EhrkeE Mihich
Jan 1, 1983·International Journal of Immunopharmacology·M J EhrkeE Mihich

Related Concepts

Related Feeds

Cancer Biology: Molecular Imaging

Molecular imaging enables noninvasive imaging of key molecules that are crucial to tumor biology. Discover the latest research in molecular imaging in cancer biology in this feed.

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.