Modification of the pH dependence of animal and plant transport ATPases by sulfated polysaccharides

Biochemical and Biophysical Research Communications
J B RochaLeopoldo de Meis

Abstract

The effects of heparin and dextran sulfate 8,000 on two isoforms of the sarco/endoplasmic reticulum Ca(2+)-ATPase of different animal tissues and on the corn root H(+)-ATPase were examined. In the absence of sulfated polysaccharides the pH profile's of the three transport ATPases were quite different, but after the addition of heparin or dextran sulfate 8,000 the pH profiles of the three enzymes became similar, all showed maximal activity at pH 7.0. Potassium and sodium antagonized the effects of sulfated polysaccharides on the three transport ATPases, but the antagonism was considerably reduced at acidic pH values.

References

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Citations

Aug 28, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Danielly Cristiny Ferraz da Costa, Ana Maria Landeira-Fernandez
Oct 19, 2001·The International Journal of Biochemistry & Cell Biology·V P VieiraM R Schetinger

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