Modifications of Hydroxyapatite by Gallium and Silver Ions-Physicochemical Characterization, Cytotoxicity and Antibacterial Evaluation.

International Journal of Molecular Sciences
Kamil PajorJoanna Kolmas

Abstract

Hydroxyapatite (HA) powders enriched with silver or gallium ions or both were synthesized by two different routes: standard precipitation and the solid-state method. The powders were characterized by using several methods: inductively coupled plasma optical emission spectrometry (ICP-OES), powder X-ray diffractometry (PXRD), transmission electron microscopy (TEM), infrared spectroscopy (FT-IR) and solid-state nuclear magnetic resonance spectroscopy (ssNMR). The effects of enrichment of the HAs in Ag+ or Ga3+ or both on in vitro cytotoxicity and microbiological activity were discussed. PXRD experiments showed that the samples obtained by the wet method consisted of single-phase nanocrystalline HA, while the samples prepared via the solid-state method are microcrystalline with a small amount of calcium oxide. The introduction of higher amounts of silver ions was found to be more effective than enriching HA with small amounts of Ag+. Gallium and silver ions were found not to affect the lattice parameters. Ga3+ affected the crystallinity of the samples as well as the content of structural hydroxyl groups. Among samples synthesized by the wet method, only one (5Ag-HAw) was cytotoxic, whereas all Ga-containing samples obtained by the...Continue Reading

References

Aug 2, 2002·Clinical Orthopaedics and Related Research·Mark E ShirtliffJon T Mader
Sep 11, 2002·Journal of Biomedical Materials Research·S Koutsopoulos
Jan 1, 1997·Journal of Materials Science. Materials in Medicine·I Rehman, W Bonfield
Dec 15, 2005·The International Journal of Artificial Organs·C R ArciolaL Montanaro
Jun 29, 2006·Current Opinion in Infectious Diseases·Andrej Trampuz, Andreas F Widmer
Nov 24, 2006·Journal of Materials Science. Materials in Medicine·Giancarlo CelottiCaterina Ducati
Dec 9, 2009·Biomaterials·Sergey V Dorozhkin
Jun 16, 2010·Drug Discovery Today·Elise VerronJean-Michel Bouler
Jul 14, 2010·International Journal of Environmental Research and Public Health·Christopher R Chitambar
Feb 2, 2011·The Journal of Bone and Joint Surgery. British Volume·M El-HusseinyF S Haddad
Jul 29, 2011·Inorganic Chemistry·Charlotte MellierPascal Janvier
Jan 1, 2005·Topics in Current Chemistry·Waclaw Kolodziejski
Apr 27, 2012·Deutsches Ärzteblatt International·Gerhard WalterReinhard Hoffmann
Jun 19, 2013·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Kristel MijnendonckxRob Van Houdt
Aug 31, 2013·Journal of Nanoparticle Research : an Interdisciplinary Forum for Nanoscale Science and Technology·Lukasz Pajchel, Waclaw Kolodziejski
Mar 19, 2014·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·D GopiL Kavitha
Apr 5, 2014·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Ana Lucia L LimaUNKNOWN Diretrizes Panamericanas para el Tratamiento de las Osteomielitis e Infecciones de Tejidos Blandos Group
Jun 21, 2014·BioMed Research International·Joanna KolmasDagmara Kwiatkowska-Różycka
May 7, 2015·Nanomedicine : Nanotechnology, Biology, and Medicine·Poon Nian LimEng San Thian
May 23, 2015·International Journal of Molecular Sciences·Joanna KolmasMarcin Sobczak
Jun 16, 2015·Acta Biomaterialia·Charlotte MellierBruno Bujoli
Jun 29, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Chao ShiYingchun Zhu
Mar 12, 2016·Bulletin of the World Health Organization·Thomas G WeiserAtul A Gawande
Dec 28, 2012·Science and Technology of Advanced Materials·Masahiro Okada, Tsutomu Furuzono
Dec 19, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Zhen GengXianjin Yang
Mar 4, 2017·Materials Science & Engineering. C, Materials for Biological Applications·Joanna KolmasEliza Kurek
Oct 18, 2018·Acta Cirúrgica Brasileira·Pedro Carvalho CassinoRuy de Araujo Caldas
Nov 21, 2018·Antimicrobial Resistance and Infection Control·Marie DavatIlker Uçkay
May 28, 2019·Open Forum Infectious Diseases·Nicolás W Cortés-Penfield, Prathit A Kulkarni
Nov 22, 2019·Antimicrobial Resistance and Infection Control·Moi Lin LingKoji Yamada
Dec 13, 2019·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·R AnderssonD Ansari
Feb 13, 2020·The Journal of Arthroplasty·Karan GoswamiJavad Parvizi

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Citations

Mar 20, 2021·ACS Biomaterials Science & Engineering·Anna DonnadioMorena Nocchetti

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Methods Mentioned

BETA
NMR
nuclear magnetic response
transmission electron microscopy
X-ray
infrared spectroscopy
nuclear magnetic resonance

Software Mentioned

NUTS
Synergy
KaleidaGraph
TOPAS

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