Modified Medical Research Council scale vs Baseline Dyspnea Index to evaluate dyspnea in chronic obstructive pulmonary disease

International Journal of Chronic Obstructive Pulmonary Disease
T PerezInitiatives BPCO Scientific Committee

Abstract

Assessment of dyspnea in COPD patients relies in clinical practice on the modified Medical Research Council (mMRC) scale, whereas the Baseline Dyspnea Index (BDI) is mainly used in clinical trials. Little is known on the correspondence between the two methods. Cross-sectional analysis was carried out on data from the French COPD cohort Initiatives BPCO. Dyspnea was assessed by the mMRC scale and the BDI. Spirometry, plethysmography, Hospital Anxiety-Depression Scale, St George's Respiratory Questionnaire, exacerbation rates, and physician-diagnosed comorbidities were obtained. Correlations between mMRC and BDI scores were assessed using Spearman's correlation coefficient. An ordinal response model was used to examine the contribution of clinical data and lung function parameters to mMRC and BDI scores. Data are given as median (interquartile ranges, [IQR]). Two-hundred thirty-nine COPD subjects were analyzed (men 78%, age 65.0 years [57.0; 73.0], forced expiratory volume in 1 second [FEV1] 48% predicted [34; 67]). The mMRC grade and BDI score were, respectively, 1 [1-3] and 6 [4-8]. Both BDI and mMRC scores were significantly correlated at the group level (rho =-0.67; P<0.0001), but analysis of individual data revealed a large ...Continue Reading

Citations

Mar 10, 2017·Postgraduate Medicine·Antonio Anzueto, Marc Miravitlles
Apr 15, 2016·The European Respiratory Journal·Capucine Morélot-PanziniThomas Similowski
Mar 1, 2019·ERJ Open Research·Konstantinos KostikasClaus F Vogelmeier
Dec 12, 2018·Annals of the American Thoracic Society·Nour AssadAkshay Sood
Sep 25, 2017·Journal of Cardiovascular Medicine·Mohamad Amer AlaitiSanjay Rajagopalan
Dec 7, 2017·COPD·S ZewariY Heijdra
Oct 29, 2019·Journal of Back and Musculoskeletal Rehabilitation·Betul TaspinarCihan C Aksoy
Sep 16, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Sarath RajuGregory D Kirk
Dec 17, 2020·Respiratory Medicine and Research·E H OuaalayaC Raherison-Semjen
May 13, 2018·Journal of Pain and Symptom Management·Jacob SandbergMagnus Ekström
Mar 17, 2020·Biochemical and Biophysical Research Communications·Matthias CatteauPascal Pomiès

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