Abstract
The aim of this study was to explore a modified model to simplify the diagnostic process for American College of Radiology Breast Imaging Reporting and Data System category 3 to 5 breast lesions and evaluate the model's diagnostic efficacy. A retrospective review was conducted of breast lesions examined by B-mode ultrasound (US) and contrast-enhanced ultrasound (CEUS) and diagnosed by histopathologic examination from October 2016 to August 2019. The US characteristics of a combined model (US + CEUS model) with relatively high diagnostic value were selected by a lasso regression analysis to establish a modified model. Two nomograms were developed. The results were internally validated by bootstrap resampling. Overall, 206 breast lesions in 198 patients, 136 benign and 70 malignant, were included. Ultrasound characteristics included in the modified model were shape, margin, microcalcification, enhanced intensity, enhanced scope, and enhanced time. For the US + CEUS model and modified model, sensitivities were 94.3% and 93.3%; specificities were 85.9% and 81.4%; accuracies were 89.3% and 88.7% and areas under the curve were 0.957 and 0.944, respectively. No statistically significant differences were seen in the diagnostic efficaci...Continue Reading
References
Feb 24, 2001·Cancer Metastasis Reviews·M Nesbit
Oct 6, 2001·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·A OzdemirS Işik
Oct 16, 2002·Human Pathology·Lydia NakopoulouAndroniki Louvrou
Mar 25, 2006·Research in Veterinary Science·F MillantaA Poli
Dec 14, 2006·European Journal of Radiology·Daniel Vanel
Mar 1, 2012·Cell Biochemistry and Biophysics·Du WenhuaTao Li
Dec 29, 2012·Current Pharmaceutical Design·Feng YangYan Lin
Oct 24, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Jian LiuTing Xie
Dec 30, 2014·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·He LiuQian Yang
Feb 6, 2015·CA: a Cancer Journal for Clinicians·Lindsey A TorreAhmedin Jemal
Nov 19, 2015·JAMA Surgery·Zhengqing LeiFeng Shen
Apr 16, 2016·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Ajay Aroor RaoHaydee Ojeda-Fournier
May 5, 2016·Japanese Journal of Radiology·Ritsuko FujimitsuKengo Yoshimitsu
Jul 1, 2016·World Journal of Radiology·Jun LuoJing-Qiao Lu
Aug 10, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Xuelei MaWenwu Ling
Oct 21, 2016·European Radiology·Xiaoyun XiaoBaoming Luo
Jan 31, 2017·Diagnostic and Interventional Imaging·D A SpakB E Dogan
Aug 26, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Jinhua DingWeizhu Wu
Jun 25, 2018·In Vivo·Irene VrakaAristides Antoniou
Nov 7, 2018·European Journal of Radiology·Jing LiTong Xu
Jan 1, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Sandy C LeeLinda Hovanessian-Larsen
Jan 12, 2019·Investigative Radiology·Panagiotis KapetasPascal A T Baltzer
Feb 14, 2019·Clinical Radiology·J ShangS-J Chang
Mar 12, 2019·Clinical Hemorheology and Microcirculation·Juan QuanPintong Huang
Mar 22, 2019·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Hui-Hong JiangMou-Bin Lin
Apr 3, 2019·Cancer Management and Research·Lina TangJun Luo
Apr 18, 2019·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Ah Young ParkBo Kyoung Seo
Aug 17, 2019·Scientific Reports·Wei-Quan LuoWei Wang