Modified vertical rectus abdominis myocutaneous flap vaginal reconstruction: an analysis of surgical outcomes

Gynecologic Oncology
Jessica L BergerPamela T Soliman

Abstract

To examine the early and late flap related morbidity and associated risk factors in patients with modified vertical rectus abdominis myocutaneous (VRAM) flap neovaginal reconstruction at the time of pelvic exenteration for gynecologic malignancy. From January 1993 to January 2011, all patients were identified who underwent anterior, posterior, or total pelvic exenteration with VRAM flap neovaginal reconstruction. Patient records were systematically reviewed and demographic, clinicopathologic, operative details, flap related complications, and risk factors for wound healing were recorded and statistical analysis performed. 46 patients were identified who underwent exenteration with VRAM flap vaginal reconstruction. A risk factor for poor healing including obesity, diabetes, smoking, prior radiation, previous abdominal surgery, or poor nutritional status was present in 38 (82.6%) patients, and 24 (52.2%) had two or more risk factors. Flap complications occurred in 9 (19.6%) patients, one with complete flap necrosis that required re-operation, two with superficial flap necrosis, and three with superficial flap separation. Three patients (6.5%) suffered from vaginal stenosis, one of which was complete. Anterior abdominal wound sepa...Continue Reading

References

May 1, 1989·American Journal of Obstetrics and Gynecology·L J CopelandC L Edwards
Jun 1, 1996·Gynecologic Oncology·J W CarlsonL B Twiggs
Mar 2, 2005·Obstetrics and Gynecology·Anil K SoodCharles Levenback
May 11, 2005·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·J T SoperD L Clarke-Pearson
Oct 23, 2008·Annals of Surgical Oncology·Matías JuradoEmilio Garcia-Tutor
Jan 1, 2009·Plastic and Reconstructive Surgery·Rebecca A Nelson, Charles E Butler

❮ Previous
Next ❯

Citations

Dec 6, 2014·Critical Reviews in Oncology/hematology·Angiolo GadducciClaudia Sergiampietri
Oct 13, 2014·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Ilkka S KaartinenHannu O Kuokkanen
May 20, 2014·Gynecologic Oncology·Albert H ChaoJeffrey M Fowler
Sep 2, 2016·Case Reports in Plastic Surgery & Hand Surgery·C RubinoG C Accarino
Nov 3, 2016·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A R MortensenP Christensen
Aug 17, 2018·Annals of Plastic Surgery·Umberto CortinovisFrancesco Raspagliesi
Jan 9, 2018·Annals of Plastic Surgery·Joke HellingaYassir Eltahir
Jul 23, 2014·Current Opinion in Oncology·Manpreet KaurIgnace Vergote
Nov 28, 2013·Plastic and Reconstructive Surgery·Shan Shan QiuBernardo Hontanilla
Dec 30, 2014·Plastic and Reconstructive Surgery·Eric D WangHani Sbitany
Mar 13, 2019·Plastic and Reconstructive Surgery. Global Open·Lisa M BlockMichael L Bentz
Apr 25, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J WoodfieldJ Ly
Apr 24, 2021·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·David ChiSamuel J Lin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.