Modifying effects of health status, physiological, and dosimetric factors on extrapulmonary organ distribution and excretion of inhaled plutonium in workers at the Mayak Production Association

Health Physics
K SuslovaM P Krahenbuhl

Abstract

This paper summarizes the systemic organ distribution of plutonium in workers exposed by chronic inhalation at the Mayak Production Association (MPA). Using results of radiochemical measurements in soft tissue and bone samples collected at autopsy of 853 autopsy cases, this paper provides data on the effects of various chronic diseases and malignant tumors as well as exposure time, age, sex, and body burden on systemic retention of plutonium in 22 extrapulmonary organs and on the urinary excretion rate of the nuclide. Some aspects of this work have been reported already. The results of present autopsy studies showed that liver pathology accompanied by strong fatty dystrophy of hepatocytes results in a significant relative decrease in the fraction of systemic plutonium in the liver and contravariant increase in the skeletal fraction. The average fractions of systemic plutonium in the liver and the skeleton of those MPA workers were 15% and 75%, respectively, in comparison with 47% and 45% in healthy individuals. Some of the plutonium also redistributed from the liver via blood to other systemic soft tissues. Plutonium not redistributed was excreted with urine. The results of multivariate regression analysis indicated some time-r...Continue Reading

References

Oct 1, 1979·Health Physics·G L VoelzW D Moss
Mar 24, 1975·Clinica Chimica Acta; International Journal of Clinical Chemistry·M E De BroeR J Wieme
Feb 1, 1992·Health Physics·G N TaylorS C Miller
Sep 1, 1991·Health Physics·G N TaylorF F Hahn
Apr 1, 1984·Health Physics·R G ThomasJ F McInroy
Jan 1, 1983·Health Physics·N P SinghS A Ibrahim
Aug 1, 1980·Health Physics·H MussaloJ K Miettinen
Aug 24, 2000·Radiation Research·N A KoshurnikovaV V Vostrotin
Aug 24, 2000·Radiation Research·E S GilbertV V Vostrotin
Dec 7, 2002·Health Physics·C Rick Jones
Apr 1, 1977·Multivariate Behavioral Research·P Cohen, J Cohen

❮ Previous
Next ❯

Citations

Aug 19, 2007·Health Physics·E K VasilenkoV Vostrotin
Oct 3, 2018·International Journal of Environmental Research and Public Health·Narongchai AutsavaprompornShinji Tokonami
Nov 21, 2018·Health Psychology Review·Sulamunn R M ColemanJoshua M Smyth
Jan 12, 2007·The Protein Journal·Sanjeeva J WijeyesakereJeanne A Stuckey
Mar 16, 2012·Health Physics·Klara G SuslovaScott C Miller
Oct 13, 2019·Journal of Environmental Radioactivity·S A RomanovV F Khokhryakov
Oct 2, 2021·Radiation Protection Dosimetry·Deepesh PoudelSergei Y Tolmachev

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.