Modulating β-carotene bioaccessibility by controlling oil composition and concentration in edible nanoemulsions

Food Chemistry
L Salvia-TrujilloDavid Julian McClements

Abstract

Diets rich in carotenoids have been correlated with a reduced risk of developing certain types of chronic diseases, but these bioactive components have low intestinal absorption due to their hydrophobic nature. The aim of this work was to study the effect of carrier oil composition (medium-chain triglyceride (MCT) to long-chain triglyceride (LCT) ratio) and total carrier oil concentration (1% or 4% w/w) on the physical stability, lipid digestibility and bioaccessibility of β-carotene-loaded nanoemulsions, using a simulated digestion process. Lipolysis led to an appreciable increase in the size and negative charge on the particles in the system. The total fraction of triacylglycerols converted to free fatty acids decreased as the percentage of LCT within the lipid phase increased, particularly for the nanoemulsions with higher fat contents. There was an increase in β-carotene bioaccessibility as the LCT within the lipid phase increased for low fat nanoemulsions, which was attributed to the increased solubilisation capacity of mixed micelles formed by LCT. β-carotene bioaccessibility showed a complex relationship on LCT content for high fat nanoemulsions, due to the opposing effects of lipid digestion and micelle solubilisation. ...Continue Reading

References

Feb 1, 1991·Journal of Cardiovascular Pharmacology·M R PrinceG M LaMuraglia
Jan 1, 1983·Annual Review of Physiology·M C CareyC M Bliss
Aug 26, 1998·Annual Review of Nutrition·J J Castenmiller, C E West
Jun 11, 2002·Annual Review of Nutrition·Kyung-Jin Yeum, Robert M Russell
Jul 24, 2002·Nutrition in Clinical Care : an Official Publication of Tufts University·Elizabeth J Johnson
Dec 5, 2003·Progress in Lipid Research·Huiling Mu, Carl-Erik Høy
Oct 19, 2004·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Janne Ørskov ChristensenAnette Mullertz
Nov 9, 2006·Journal of Agricultural and Food Chemistry·Emmanuelle ReboulPatrick Borel
Dec 30, 2006·Molecular Nutrition & Food Research·Lina Yonekura, Akihiko Nagao
Feb 27, 2007·Molecular Aspects of Medicine·Attilio Rigotti
Mar 14, 2007·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·A V Rao, L G Rao
Jul 10, 2007·Advanced Drug Delivery Reviews·David J Hauss
Oct 12, 2007·Journal of Agricultural and Food Chemistry·Tianyao HuoMark L Failla
Dec 11, 2007·Advanced Drug Delivery Reviews·Colin W Pouton, Christopher J H Porter
Dec 25, 2007·Advanced Drug Delivery Reviews·Christopher J H PorterWilliam N Charman
May 24, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Arik Dahan, Amnon Hoffman
Aug 12, 2008·Advances in Colloid and Interface Science·P ReisR Miller
Nov 28, 2008·Molecular Nutrition & Food Research·Giuseppe MaianiUlrich Schlemmer
Jan 1, 2009·Progress in Lipid Research·Harjinder SinghDavid Horne
Jun 2, 2009·Critical Reviews in Food Science and Nutrition·David Julian McClementsJochen Weiss
Jun 15, 2010·Critical Reviews in Food Science and Nutrition·Caitlin S BoonEric A Decker
Jun 19, 2010·Journal of Agricultural and Food Chemistry·Yan Li, David Julian McClements
Jul 20, 2010·Advances in Colloid and Interface Science·David Julian McClements, Yan Li
Jun 4, 2011·Molecular Nutrition & Food Research·Amir Malaki NikAmanda J Wright
Sep 8, 2012·Food Chemistry·Cheng QianDavid Julian McClements

❮ Previous
Next ❯

Citations

Dec 3, 2015·Journal of Agricultural and Food Chemistry·Jiang YiLiqing Zhao
Sep 12, 2015·Journal of Agricultural and Food Chemistry·Xuan LiuDavid Julian McClements
Dec 4, 2014·Food Chemistry·Saehun MunDavid Julian McClements
Jan 21, 2015·Critical Reviews in Food Science and Nutrition·Touseef Ahmed WaniMudasir Ahmad Shagoo
Nov 20, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Stefan SalentinigBen J Boyd
May 21, 2016·Journal of Agricultural and Food Chemistry·Laura Salvia-Trujillo, David Julian McClements
Jan 27, 2017·Annual Review of Food Science and Technology·Laura Salvia-TrujilloOlga Martín-Belloso
Feb 24, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Bulei ShengHui Rong
Jan 19, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gong-Liang ZhangHong-Man Hou
Jan 7, 2020·Annual Review of Food Science and Technology·David Julian McClements
Jan 14, 2016·Nanomaterials·Laura Salvia-TrujilloDavid Julian McClements
Jan 1, 2014·Frontiers in Nutrition·Isabel Odriozola-SerranoOlga Martín-Belloso
Apr 11, 2020·Foods·Júlia Teixé-RoigOlga Martín-Belloso
Dec 30, 2020·Progress in Lipid Research·David Julian McClements
Feb 3, 2021·Comprehensive Reviews in Food Science and Food Safety·Pheakdey YunNaphaporn Chiewchan
Oct 23, 2020·Journal of Food Science and Technology·Junhee NoSaehun Mun
Mar 1, 2014·Comprehensive Reviews in Food Science and Food Safety·Juana M Carbonell-CapellaAna Frígola
Sep 1, 2015·Food Research International·Ruojie ZhangDavid Julian McClements

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Epigenetics Insights from Twin Studies

Find the latest research on epigenetics and twin studies here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.