Modulating offspring responses: concerted effects of stress and immunogenic challenge in the parental generation.

The Journal of Experimental Biology
Octavio GiayettoF N Nazar

Abstract

The perception, processing and response to environmental challenges involves the activation of the immuno-neuroendocrine (INE) interplay. Concerted environmental challenges might induce trade-off when resource allocation to one trait occurs at the expense of another, also producing potential transgenerational effects in the offspring. We evaluated whether concerted challenges, in the form of an immune inoculum against inactivated Salmonella enteritidis (immune challenge, ICH) and a chronic heat stress (CHS) exposure on adult Japanese quail, modulate the INE responses of the parental generation and their offspring. Adults were inoculated and later exposed to a CHS along nine consecutive days. For the last 5 days of the CHS, eggs were collected for incubation. Chicks were identified according to their parental treatments and remained undisturbed. Induced inflammatory response, heterophil/lymphocyte (H/L) ratio and specific humoral response against sheep red blood cells (SRBC) were evaluated in both generations. Regardless of the ICH, stressed adults showed a reduced inflammatory response and an elevated H/L ratio compared with controls. In offspring, the inflammatory response was elevated and the specific SRBC antibody titres wer...Continue Reading

References

Mar 29, 2000·Poultry Science·S Puvadolpirod, J P Thaxton
Aug 15, 2000·Neuroscience and Biobehavioral Reviews·S L Klein
Aug 7, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·R GlaserJ K Kiecolt-Glaser
Feb 28, 2002·Annual Review of Immunology·Jeanette I WebsterEsther M Sternberg
Apr 22, 2003·The American Naturalist·Camille BonneaudGabriele Sorci
Jan 30, 1959·Science·C A PADGETT, W D IVEY
Dec 3, 2003·Trends in Parasitology·Gregory J Sandland, Dennis J Minchella
Jul 17, 2004·Proceedings. Biological Sciences·Sveinn Are HanssenKjell Einar Erikstad
Jul 22, 2004·Annals of the New York Academy of Sciences·Ilia J Elenkov
Jul 24, 2004·Journal of Evolutionary Biology·A Schwartz, J C Koella
Jan 25, 2005·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·L Michael Romero, J Michael Reed
Mar 3, 2005·Biological Psychology·Brigitte M Kudielka, Clemens Kirschbaum
Oct 12, 2005·Journal of Experimental Zoology. Part A, Comparative Experimental Biology·Nicola SainoAnders Pape Møller
Aug 5, 2006·The Journal of Experimental Biology·Noah T Owen-Ashley, John C Wingfield
Sep 9, 2006·Proceedings. Biological Sciences·Jennifer L GrindstaffMartin Stjernman
May 15, 2007·Poultry Science·I BedanovaV Vecerek
Jul 20, 2007·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Lynn B MartinRandy J Nelson
Oct 24, 2007·British Poultry Science·K C Klasing
Feb 19, 2008·Cellular Immunology·Jeanette I Webster Marketon, Ronald Glaser
Apr 9, 2008·Brain, Behavior, and Immunity·J M Koolhaas
May 9, 2008·Frontiers in Neuroendocrinology·Frances A Champagne
Aug 19, 2008·The American Naturalist·Marlene Zuk, Andrew M Stoehr
Oct 10, 2008·Proceedings. Biological Sciences·Eunice H ChinGary Burness
Oct 25, 2008·Lab Animal·David HussRusty Lansford
May 28, 2009·Hormones and Behavior·L Michael RomeroNicole E Cyr
Oct 15, 2009·Frontiers in Behavioral Neuroscience·Elizabeth C Cottrell, Jonathan R Seckl
Jan 16, 2010·Science·Akiko Iwasaki, Ruslan Medzhitov
Jan 30, 2010·The American Naturalist·Jonathan J Storm, Steven L Lima
Nov 3, 2010·Stress : the International Journal on the Biology of Stress·F N Nazar, R H Marin
Dec 1, 2006·Integrative and Comparative Biology·Kelly A Lee
Jan 3, 2012·Physiology & Behavior·Esther Nederhof, Mathias V Schmidt

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.