Modulation and predictors of periprosthetic bone mineral density following total knee arthroplasty

BioMed Research International
Anett Mau-MoellerRalf Skripitz

Abstract

Total knee arthroplasty (TKA) leads to a loss of periprosthetic bone mineral density (BMD). Great importance is attached to the prevention of periprosthetic bone loss with a view to ensuring a long service life of the prosthesis. In order to provide appropriate recommendations for preventive movement therapy measures to combat peri-implant bone loss, it is necessary to know the predictors of periprosthetic BMD. The aim of this study was (1) to determine the change of periprosthetic BMD of the femur and tibia and (2) to analyse the effects of different predictors on periprosthetic BMD. Twenty-three patients with primary TKA were evaluated 10 days and 3 months postoperatively. The data analysis comprised (1) the change in periprosthetic BMD from pretest to posttest and (2) the correlations between BMD and the variables isometric maximum voluntary force, lean mass, physical activity (step count), and BMI using multiple linear regression and structural equation modelling (SEM). BMD of the distal femur was significantly reduced by 19.7% (P = 0.008) 3 months after surgery, while no changes were found in BMD of the tibia. The results of SEM demonstrate that 55% of the BMD variance was explained by the model (χ(2) = 0.002; df = 1; P = ...Continue Reading

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Citations

Dec 8, 2017·Clinical Reviews in Bone and Mineral Metabolism·M GundryK Knapp
Jul 30, 2018·BMC Musculoskeletal Disorders·Kristine GodziukMary Forhan
Sep 2, 2018·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T BlatyP Anderson
Mar 21, 2021·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·E von VopeliusF T Beil

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Methods Mentioned

BETA
X-ray
force measurement

Software Mentioned

enCORE
Lunar enCORE
Power
MyoResearch Master Edition
activPAL
Lunar
SPSS
AMOS
SEM

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