PMID: 3762106Sep 1, 1986Paper

Modulation detection by patients with eighth-nerve tumors

Journal of Speech and Hearing Research
C Formby

Abstract

Detection thresholds for sinusoidally amplitude-modulated broad-band noise were measured as a function of modulation frequency for 4 normally hearing listeners and for 6 patients suffering eighth-nerve tumors. Measurements were obtained using a method-of-adjustment (MOA) procedure. On average, the threshold values revealed that more modulation was needed across all modulation frequencies for the patients' affected ears relative to either the normally hearing listeners or the patients' better ears. The cutoff frequency derived from the average modulation-threshhold function (MTF) for the affected ears was about half the normal value. For a simple lowpass-filter model of the process, the latter result suggested a doubling of the auditory time constant in the affected ears. These patients, on average, exhibited the characteristic high-frequency audiometric hearing loss most often associated with eighth-nerve tumors. Their MTFs closely resembled MTFs described previously for high-frequency audiometric hearing loss. The results of statistical analyses suggested that high frequency audiometric hearing loss, irrespective of other influences, is the most parsimonious explanation for the increased modulation thresholds measured for the ...Continue Reading

Citations

Jun 1, 1992·Journal of Speech and Hearing Research·S P Bacon, R M Gleitman
Jan 1, 1987·Audiology : Official Organ of the International Society of Audiology·C Formby
Jun 14, 1993·Annals of the New York Academy of Sciences·B C Moore
Dec 24, 2004·Journal of Neurophysiology·Fan-Gang ZengArnold Starr
Jul 22, 1998·The Journal of the Acoustical Society of America·L M RichardsonG M Clark
Aug 24, 2000·The Journal of the Acoustical Society of America·A KohlrauschT Dau
Aug 3, 2005·Journal of the Association for Research in Otolaryngology : JARO·John J Galvin, Qian-Jie Fu

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