Modulation index for VMAT considering both mechanical and dose calculation uncertainties

Physics in Medicine and Biology
Jong Min ParkHyoungnyoun Kim

Abstract

The aim of this study is to present a modulation index considering both mechanical and dose calculation uncertainties for volumetric modulated arc therapy (VMAT). As a modulation index considering only mechanical uncertainty of VMAT, MIt has been previously suggested. In this study, we developed a weighting factor which represents dose calculation uncertainty based on the aperture shapes of fluence maps at every control point of VMAT plans. In order to calculate the weighting factor, the thinning algorithm of image processing techniques was applied to measure field aperture irregularity. By combining this weighting factor with the previously suggested modulation index, MIt, comprehensive modulation index (MIc) was designed. To evaluate the performance of MIc, gamma passing rates, differences in mechanical parameters between plans and log files and differences in dose-volume parameters between plans and the plans reconstructed from log files were acquired with a total of 52 VMAT plans. Spearman's correlation coefficients (rs) between the values of MIc and measures of VMAT delivery accuracy were calculated. The rs values of MIc (f = 0.5) to global gamma passing rates with 2%/2 mm, 1%/2 mm and 2%/1 mm were  -0.728,-0.847 and  -0.6...Continue Reading

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Citations

Jul 12, 2019·The British Journal of Radiology·Sophie ChiavassaAlexandra Moignier
May 1, 2019·Journal of Applied Clinical Medical Physics·Jong Min ParkSo-Yeon Park
Dec 25, 2019·Radiation Oncology·Jong Min ParkSo-Yeon Park
Apr 21, 2020·Nihon Hoshasen Gijutsu Gakkai zasshi·Tatsuya KamimaTomoharu Sato
Jan 14, 2017·Australasian Physical & Engineering Sciences in Medicine·Jong Min ParkJin Ho Kim
Dec 14, 2018·Radiation Oncology·So-Yeon ParkJong Min Park
Jul 11, 2020·Physical and Engineering Sciences in Medicine·Mikoto TamuraHajime Monzen
Dec 18, 2020·Medical Physics·Laura MasiLorenzo Livi
Mar 19, 2021·Journal of Applied Clinical Medical Physics·Stefano PifferCinzia Talamonti
Sep 14, 2019·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Mikaël AntoineJérôme Caron
Apr 27, 2021·Physics and Imaging in Radiation Oncology·Julia Götstedt, Anna Bäck

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