Modulation of cerebral blood flow in the human auditory cortex during speech: role of motor-to-sensory discharges

The European Journal of Neuroscience
T PausA C Evans

Abstract

To investigate mechanisms of audio-vocal interactions in the human brain, we studied the effect of speech output on modulation of neuronal activity in the auditory cortex. The modulation was assessed indirectly by measuring changes in cerebral blood flow (CBF) during unvoiced speech (whispering). Using positron emission tomography (PET), CBF was measured in eight volunteers as they uttered syllables at each of seven rates (30, 50, 70, 90, 110, 130 or 150/min) during each of the seven 60-s PET scans. Low-intensity white noise was used throughout scanning to mask auditory input contingent on the whispering. We found that, as a function of the increasing syllable rate, CBF increased in the left primary face area, the upper pons, the left planum temporale and the left posterior perisylvian cortex. The latter two regions contain secondary auditory cortex and previously have been implicated in the processing of speech sounds. We conclude that, in the absence of speech-contingent auditory input, the modulation of CBF in the auditory cortex is mediated by motor-to-sensory discharges. As such, it extends our previous findings of oculomotor corollary discharges to the audio-vocal domain.

References

Jun 1, 1978·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·F BollerJ L Mack
Jan 1, 1978·Neuropsychologia·F Boller, P Marcie
Jan 1, 1977·Neuropsychologia·S E BlumsteinH Goodglass
Jan 1, 1976·Vision Research·J K StevensA C Rosenquist
Jul 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·F J NorthingtonR M Berne
Nov 1, 1992·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·K J WorsleyP Neelin
Dec 1, 1992·Brain : a Journal of Neurology·J F DémonetR Frackowiak
Jan 1, 1991·Experimental Brain Research·A Kirzinger, U Jürgens
Jul 1, 1988·The Journal of Comparative Neurology·M Petrides, D N Pandya
Jul 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R G KnowlesS Moncada
Jan 1, 1989·Experimental Brain Research·O CreutzfeldtE Lettich
Sep 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·M KadekaroL Sokoloff
Dec 1, 1982·Acta Neurologica Scandinavica·G GainottiG Villa
Apr 1, 1984·Neurology·M FreedmanM A Naeser
Apr 1, 1980·The Journal of Comparative Neurology·A Galaburda, F Sanides
Jan 1, 1981·Journal of Perinatal Medicine·R Terinde
Jun 29, 1981·Brain Research·P Müller-Preuss, D Ploog
Aug 1, 1995·Journal of Neurophysiology·C DettmersR S Frackowiak
Jun 20, 1995·Proceedings of the National Academy of Sciences of the United States of America·R KawashimaP E Roland
Jul 1, 1994·Brain Research. Cognitive Brain Research·J R BinderJ S Hyde
Mar 1, 1994·Journal of Computer Assisted Tomography·D L CollinsA C Evans
Jul 1, 1993·Journal of Computer Assisted Tomography·R P WoodsS R Cherry
Mar 25, 1993·Nature·E PaulesuR S Frackowiak
Oct 1, 1963·Journal of Comparative and Physiological Psychology·R HELD, A HEIN
Dec 1, 1950·Journal of Comparative and Physiological Psychology·R W SPERRY
Jan 1, 1996·Journal of Cognitive Neuroscience·R J ZatorreA C Evans

❮ Previous
Next ❯

Citations

Mar 26, 2003·American Journal of Physical Anthropology·Philip Lieberman
Jun 5, 2001·Acta Psychologica·K G Munhall
Apr 2, 2002·Biological Psychiatry·Judith M FordWalton T Roth
Sep 6, 2002·Brain Research·Kristina Simonyan, Uwe Jürgens
May 14, 2003·Brain Research·Kristina Simonyan, Uwe Jürgens
Dec 24, 2003·Journal of Psychiatric Research·Judith M Ford, Daniel H Mathalon
Feb 22, 2002·Neuroscience and Biobehavioral Reviews·Uwe Jürgens
Jan 22, 2003·Trends in Neurosciences·Sophie K Scott, Ingrid S Johnsrude
May 18, 1999·Neuroscience Letters·J NumminenR Hari
Mar 29, 2002·Brain Research. Cognitive Brain Research·Riikka MöttönenMikko Sams
Nov 16, 2002·Brain Research. Cognitive Brain Research·Ardi Roelofs, Peter Hagoort
Mar 31, 2000·Trends in Cognitive Sciences·G Hickok, D Poeppel
Jan 3, 2001·Brain : a Journal of Neurology·R J WiseE A Warburton
Nov 12, 2009·Brain : a Journal of Neurology·Jane E WarrenRichard J S Wise
Apr 24, 2002·Journal of Cognitive Neuroscience·Burkhard MaessWillem J M Levelt
Mar 11, 2011·PloS One·Jeremy D W GreenleeMatthew A Howard
Nov 13, 2012·PloS One·Amanda S TherrienRamesh Balasubramaniam
Jan 29, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jaakko KauramäkiMikko Sams
Sep 6, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Anders NelsonRichard Mooney
Oct 31, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jon T Sakata, Michael S Brainard
Feb 9, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Oiwi Parker JonesCathy J Price
Aug 3, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Steven J Eliades, Xiaoqin Wang
Mar 8, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Zane Z ZhengIngrid S Johnsrude
Oct 16, 2008·Brain : a Journal of Neurology·Iris E C SommerRené S Kahn
Nov 22, 2001·Proceedings of the National Academy of Sciences of the United States of America·M IacoboniG Rizzolatti
Jan 8, 2014·Journal of Cognitive Neuroscience·Nicole MalfaitAnne Caclin
May 10, 2006·Proceedings of the National Academy of Sciences of the United States of America·Friedemann PulvermüllerYury Shtyrov
May 18, 2013·Cerebral Cortex·Alexander M ChanSydney S Cash
Jun 28, 2011·AJNR. American Journal of Neuroradiology·D RivaA Erbetta
Dec 3, 2014·Cerebral Cortex·Malte R SchomersFriedemann Pulvermüller
Jan 17, 2004·The European Journal of Neuroscience·Jennifer BarrettTomás Paus
Sep 10, 2015·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·G TamburriniC Di Rocco
Jul 9, 1998·Brain and Language·K M KurowskiH Mathison
Nov 5, 2014·Frontiers in Neuroscience·Daniel S ScholzEckart O Altenmüller
Jun 25, 2013·The Behavioral and Brain Sciences·Martin J Pickering, Simon Garrod
Jul 17, 2016·NeuroImage·Christopher J Markiewicz, Jason W Bohland
Mar 3, 2015·The European Journal of Neuroscience·Erich SchrögerIria SanMiguel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.