Modulation of concanavalin A-induced lymphocyte stimulation by human low-density lipoproteins

European Journal of Immunology
E R WaeltiM W Hess

Abstract

Spleen lymphocytes and T cells were stimulated by concanavalin A in the presence of various concentrations of human low-density lipoproteins (LDL). The proliferative responses were measured by [14C]thymidine incorporation. Low LDL doses (5-50 microgram/ml) significantly enhanced the stimulation of splenic lymphocytes and T cells. Further, LDL had the capacity to partially relieve the suppression produced by supraoptimal doses of concanavalin A.

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Citations

Mar 1, 1991·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M EugeneC Cabrol
Feb 15, 2001·Bulletin of Experimental Biology and Medicine·E P KiselevaI G Kovaleva

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