PMID: 20650083Jun 1, 1995Paper

Modulation of lipid peroxidation by dietary components

Toxicology in Vitro : an International Journal Published in Association with BIBRA
R Sujatha, L Srinivas

Abstract

The aqueous extracts of commonly consumed Indian spices and vegetables were tested for their antioxidant properties in human erythrocyte membranes against lipid peroxidation induced by FeSO(4)-ascorbate (10:100 mumol/system). Aqueous extracts of curry leaves (Murraya koneigii) at 10 mug/ml and of asafoetida (Ferula spp), omam (Carum ajowan) and mustard (Brassica nigra) at 300 mug/ml inhibited lipid peroxidation by 90, 85, 75 and 70%, respectively. The aqueous extracts of cabbage (Brassica oleracea), ginger (Zinziber officinale) and onion (Allium cepa) inhibited lipid peroxidation by 65, 72 and 66%, respectively. The aqueous extracts of spices were also found to inhibit the formation of diene, triene and tetraene conjugates in human erythrocyte membrane. Addition of lipid peroxides extracted from peroxidized human erythrocyte membrane substantially increased erythrocyte lysis over that caused by exposure to 0.54% saline alone. Aqueous extracts of omam, coriander seeds (Coriandrum sativum) and curry leaves, at 300 mug/ml, inhibited peroxidized lipid-induced lysis by 67, 72 and 87%, respectively. Lipid peroxides induced considerable activation of polymorphonuclear leucocytes activation and this activation was inhibited by the aque...Continue Reading

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Citations

May 22, 2009·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Ali A Shati, Fahmy G Elsaid
Apr 14, 2017·Journal of Dietary Supplements·Subramanian SuganyaBalaji Nandagopal
Dec 7, 2006·Annals of the New York Academy of Sciences·M D KontogianniC Tsigos
Mar 10, 2018·Current Drug Discovery Technologies·Surendra AgrawalPravina Gurjar
Oct 11, 2017·Pharmacognosy Reviews·Agilandeswari Devarajan, M K Mohanmarugaraja
May 26, 2021·Journal of Agricultural and Food Chemistry·Saad M AlmuhayawiAbdelrahim H A Hassan

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