Modulation of motor activity by cutaneous input: inhibition of the magnetic motor evoked potential by digital electrical stimulation

Electroencephalography and Clinical Neurophysiology
P D CloustonD Cros

Abstract

We examined the inhibitory effect of a brief train of digital (D2) electrical stimuli at 4 times perception threshold on transcranial magnetic motor evoked potentials (MEPs) recorded from abductor pollicis brevis (APB) and flexor carpi radialis (FCR) muscles ipsilateral to the side of D2 stimulation. We compared this to the inhibitory effect of ipsilateral D2 stimulation on averaged rectified EMG recorded at 10% maximum voluntary contraction and on F-responses and H-reflexes recorded from these same muscles. We also compared MEPs recorded following D2 stimulation just above perception threshold to MEPs following higher intensity D2 stimulation. As well, we assessed the effect of preceding D2 stimulation on MEPs recorded from a relaxed versus tonically contracted hand muscle. D2 stimulation elicited a triphasic response of modest MEP facilitation followed by inhibition and further facilitation. The duration and onset of MEP inhibition correlated with those of the initial period of rectified EMG inhibition, however, the magnitude of MEP inhibition was generally less than the magnitude of EMG inhibition, consistent with a greater inhibitory effect of digital afferents on smaller motor neurons. MEPs were not facilitated during the ...Continue Reading

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Citations

Dec 26, 2001·Muscle & Nerve·John A BurneJohn G L Morris
Aug 4, 2005·Experimental Brain Research·Stefano TamburinGiampietro Zanette
Apr 19, 2008·Experimental Brain Research·Markus KoflerLeopold Saltuari
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May 29, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·P Manganotti, G Zanette
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Jun 14, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Markus Kofler
Jul 21, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Michele TinazziAlfredo Berardelli
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Jul 15, 2017·Journal of Neuroengineering and Rehabilitation·Man-Zhao HaoNing Lan

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