PMID: 6983118Oct 1, 1982Paper

Modulation of mouse natural killer cell activity by the serum thymic factor

Scandinavian Journal of Immunology
P Bardos, J F Bach

Abstract

After mice had been treated with serum thymic factor (FTS), we observed an increase or a decrease in the NK activity, depending on the duration of treatment and mouse strain: an increase of C57BL/6, BALB/c, A, and nu/nu, and a decrease for NZB and CBA mice. The fact that treatment of C57BL/6 mice with FTS produces the same effects as thymectomy--that is, an increase--on the NK activity and returns the augmented NK activity of thymectomized mice to normal levels suggests that FTS has multiple effects with different results depending on the level of differentiation of the target cells. Different mechanisms of action of FTS on NK cells are discussed.

References

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Citations

Jan 1, 1988·Clinical & Experimental Metastasis·V J TomazicG E Elias
Jan 1, 1983·International Journal of Immunopharmacology·M C DokhelarJ F Bach
Jan 1, 1989·International Journal of Immunopharmacology·C FavalliE Garaci
Jan 1, 1992·International Journal of Immunopharmacology·M MuzzioliN Fabris
Nov 1, 1994·General Pharmacology·G OztürkN M Bor
Apr 26, 2003·Mechanisms of Ageing and Development·Robertina GiacconiEugenio Mocchegiani
Jan 9, 2010·Expert Opinion on Therapeutic Targets·Mário SantosAdelino Leite-Moreira
Oct 13, 2006·Experimental Gerontology·Eugenio MocchegianiMarco Malavolta
Aug 19, 2000·Endocrine Reviews·W Savino, M Dardenne
Feb 25, 2009·The Journal of Experimental Medicine·Fangming TangBana Jabri
Dec 22, 2011·The Journal of Immunology : Official Journal of the American Association of Immunologists·Pawel Kalinski
Apr 8, 2014·American Journal of Reproductive Immunology : AJRI·Gustavo F DoncelIrina Zalenskaya
Mar 7, 2017·Frontiers in Physiology·Willem J SanderCarolina H Pohl

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