Modulation of oligosynaptic cutaneous and muscle afferent reflex pathways during fictive locomotion and scratching in the cat

Journal of Neurophysiology
A M DegtyarenkoR E Burke

Abstract

We have compared state-dependent transmission through oligosynaptic (minimally disynaptic) reflex pathways from low-threshold cutaneous and muscle afferents to some flexor and extensor lumbosacral motoneurons during fictive locomotion and scratching in decerebrate unanesthetized cats. As reported in earlier work, oligosynaptic cutaneous excitatory postsynaptic potentials (EPSPs) in flexor digitorum longus (FDL) and inhibitory postsynaptic potentials (IPSPs) in extensor digitorum (EDL) longus motoneurons were enhanced markedly during the early flexion phase of fictive locomotion. We show in this paper that, in contrast, these cutaneous reflex pathways were depressed markedly during all phases of fictive scratching. On the other hand, disynaptic EPSPs produced by homonymous and synergist group I muscle afferents in flexor (tibialis anterior and EDL) motoneurons were present and strongly modulated during both fictive locomotion and scratching. During both actions, these disynaptic group I EPSPs appeared or exhibited the largest amplitude when the motoneuron membrane potential was most depolarized and the parent motor pool was active. There was an interesting exception to the simple pattern of coincident group I EPSP enhancement an...Continue Reading

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Citations

Dec 24, 1998·Journal of Neurophysiology·A M DegtyarenkoR E Burke
Feb 3, 1999·Annals of the New York Academy of Sciences·D A McCrea
Dec 24, 2005·Physiological Reviews·Serge RossignolJean-Pierre Gossard
Dec 7, 2006·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Holk CruseJosef Schmitz
Oct 9, 2015·Journal of Neurophysiology·Tuan Vu BuiCarl Farah
Aug 8, 2019·Medicine and Science in Sports and Exercise·Emma F Hodson-ToleJames M Wakeling
May 27, 2005·Journal of Neurophysiology·Jorge QuevedoDavid A McCrea
Dec 13, 2005·Journal of Neurophysiology·Jacques Duysens
Nov 18, 2017·BMC Veterinary Research·Zoe R NalborczykClare Rusbridge
Feb 3, 1999·Annals of the New York Academy of Sciences·J QuevedoD McCrea
Jul 5, 2013·Biological cybernetics·Malte SchillingHolk Cruse
Apr 27, 2011·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Alain Frigon
Jun 9, 2000·Annual Review of Physiology·K G Pearson
Aug 21, 2010·The European Journal of Neuroscience·Elzbieta Jankowska, Steve A Edgley
Sep 22, 2007·Brain Research Reviews·Elzbieta Jankowska

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