Modulation of Saccade Vigor during Value-Based Decision Making.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Thomas R ReppertReza Shadmehr


During value-based decision-making, individuals consider the various options and select the one that provides the maximum subjective value. Although the brain integrates abstract information to compute and compare these values, the only behavioral outcome is often the decision itself. However, if the options are visual stimuli, during deliberation the brain moves the eyes from one stimulus to the other. Previous work suggests that saccade vigor, i.e., peak velocity as a function of amplitude, is greater if reward is associated with the visual stimulus. This raises the possibility that vigor during the free viewing of options may be influenced by the valuation of each option. Here, humans chose between a small, immediate monetary reward and a larger but delayed reward. As the deliberation began, vigor was similar for the saccades made to the two options but diverged 0.5 s before decision time, becoming greater for the preferred option. This difference in vigor increased as a function of the difference in the subjective values that the participant assigned to the delayed and immediate options. After the decision was made, participants continued to gaze at the options, but with reduced vigor, making it possible to infer timing of ...Continue Reading


Feb 3, 2016·Proceedings of the National Academy of Sciences of the United States of America·Sung Jun JooAlexander C Huk
Mar 26, 2016·Current Opinion in Neurobiology·Joshua T Dudman, John W Krakauer
Jul 5, 2016·Current Biology : CB·Reza ShadmehrAlaa A Ahmed
Sep 1, 2016·Frontiers in Neuroscience·Ioan OprisRandall J Nelson
May 11, 2017·Psychological Science·Sanjay G ManoharMasud Husain
Jul 7, 2017·PLoS Computational Biology·Jonathan S DiamondJ Randall Flanagan
May 14, 2016·Journal of Neurophysiology·Joshua I GlaserMark A Segraves
Jan 6, 2017·Journal of Neurophysiology·Reza Shadmehr
Dec 7, 2017·Scientific Reports·Christian WolfAlexander C Schütz
Mar 15, 2018·Journal of Neurophysiology·Erik M SummersideAlaa A Ahmed
May 17, 2018·Journal of Neurophysiology·Thomas R ReppertReza Shadmehr
May 7, 2020·Journal of Neurophysiology·Tehrim YoonReza Shadmehr
Nov 10, 2017·Journal of Neurophysiology·Cécile Vullings, Laurent Madelain
Feb 23, 2018·Frontiers in Neuroscience·Sebastian S JamesKevin Gurney
Sep 22, 2018·Scientific Reports·F Javier Domínguez-ZamoraDaniel S Marigold
Mar 19, 2019·Frontiers in Psychology·Katinka van der KooijKrista E Overvliet
Jun 20, 2019·Frontiers in Psychology·Patrice RevolYves Rossetti
Sep 10, 2019·Advances in Geriatric Medicine and Research·Brian C ClarkDustin R Grooms
Oct 17, 2018·Proceedings of the National Academy of Sciences of the United States of America·Tehrim YoonReza Shadmehr
Jul 15, 2018·Scientific Reports·Bastien BerretThomas Deroche
Jul 27, 2018·Nature Communications·Joshua A SeidemanEmilio Salinas
Apr 12, 2019·Nature Human Behaviour·Dianna R AmasinoScott A Huettel
May 10, 2019·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Matthew A CarlandPaul Cisek

Related Concepts

Decision Making
Homo sapiens
Impulsive Behavior
Continuous Performance Task
Photic Stimulation

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Related Papers

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Jennie E S ChoiReza Shadmehr
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Adrian M HaithReza Shadmehr
Electromyography and Clinical Neurophysiology
L CompagnoniA Valentini
Proceedings of the National Academy of Sciences of the United States of America
Philip PärnametsDaniel C Richardson
Frontiers in Human Neuroscience
Sanjay G Manohar, Masud Husain
© 2021 Meta ULC. All rights reserved