Modulation of spatial attention by fear-conditioned stimuli: an event-related fMRI study

Neuropsychologia
J L Armony, Raymond J Dolan

Abstract

Stimuli that signal threat can capture subjects' attention, leading to more efficient detection of, and faster responses to, events occurring in that part of the environment. In the present study we explored the behavioural and anatomical correlates of the modulation of spatial attention by emotion using a fear conditioning paradigm, combined with a covert spatial orienting task. Reaction times for the detection of a peripheral target, which was preceded by brief (50ms) presentations of the visual conditioned stimulus (CS+) in either the same or opposite visual field, showed an interaction between stimulus emotionality and attention shifts. We used event-related functional magnetic resonance imaging (fMRI) to characterise the associated neural responses. Consistent with previous studies, conditioning-induced enhanced responses were observed in the amygdala and extrastriate visual cortex. The modulation of spatial attention by a conditioned stimulus was associated with enhanced activity in regions of frontal and parietal cortices previously implicated in spatial attention, as well as in the lateral orbitofrontal cortex (lOFC).

References

Apr 15, 1977·The Journal of Comparative Neurology·J E Krettek, J L Price
Sep 15, 1992·The Journal of Comparative Neurology·R J MorecraftM M Mesulam
Feb 1, 1980·The Quarterly Journal of Experimental Psychology·M I Posner
Jul 1, 1994·Cerebral Cortex·P A FilipekV S Caviness
Jul 1, 1996·Psychological Bulletin·J M WilliamsC MacLeod
Dec 25, 1995·The Journal of Comparative Neurology·S T Carmichael, J L Price
Feb 6, 1998·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·K M Stormark, K Hugdahl
Jun 3, 1998·Proceedings. Biological Sciences·J S MorrisR J Dolan
Apr 10, 1999·Journal of Cognitive Neuroscience·A C RosenJ R Binder
Jul 7, 1999·Neuroscience and Biobehavioral Reviews·M Fendt, M S Fanselow
Aug 27, 1999·Progress in Neurobiology·M Koch
Mar 4, 2000·Nature Neuroscience·J B HopfingerG R Mangun
Feb 7, 2001·Current Opinion in Neurobiology·C Büchel, R J Dolan
Apr 19, 2000·Journal of Cognitive Neuroscience·R Cabeza, L Nyberg
Jun 9, 2000·Annual Review of Neuroscience·J E LeDoux

❮ Previous
Next ❯

Citations

Feb 26, 2003·NMR in Biomedicine
May 19, 2006·Experimental Brain Research·Luis CarretiéFrancisco Mercado
Oct 28, 2008·Experimental Brain Research·Stefaan Van DammeCharles Spence
Jan 4, 2013·Experimental Brain Research·Marcus RothkirchPhilipp Sterzer
May 17, 2005·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Georg W AlpersPaul Pauli
Jun 7, 2005·Neural Networks : the Official Journal of the International Neural Network Society·David SanderKlaus R Scherer
Jun 1, 2005·Neural Networks : the Official Journal of the International Neural Network Society·John G Taylor, Nickolaos F Fragopanagos
Dec 31, 2002·Brain Research. Brain Research Reviews·David H Zald
May 22, 2003·Psychiatry Research·Nick J CouplandDavid J Nutt
Dec 22, 2005·Journal of Experimental Psychology. Human Perception and Performance·Jane E RaymondNikki Westoby
Oct 1, 2004·Emotion·Ernst H W KosterJan De Houwer
Apr 28, 2006·Emotion·Maarten MildersNiamh Donnellon
Jan 13, 2010·Psychological Review·Barbara L GanzelElaine Wethington
Feb 5, 2013·Nature Neuroscience·Christopher J PeckC Daniel Salzman
Jan 25, 2005·Nature Neuroscience·Didier GrandjeanPatrik Vuilleumier
Aug 10, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Vanessa M BrownRajendra A Morey
Nov 25, 2003·Psychological Science·Jane E RaymondNader T Tavassoli
May 17, 2013·Proceedings of the National Academy of Sciences of the United States of America·Liviu StănişorPieter R Roelfsema
Jul 19, 2006·The Quarterly Journal of Experimental Psychology : QJEP·Isabelle Blanchette
May 2, 2008·Cerebral Cortex·Benedetto De MartinoRaymond J Dolan
Jun 7, 2011·Social Cognitive and Affective Neuroscience·Sonia DoalloAnna C Nobre
Sep 27, 2005·Psychological Science·Mark J FenskeSteven P Tipper
Jun 21, 2008·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Rachel L BannermanArash Sahraie
Jun 26, 2004·Annual Review of Neuroscience·Kalanit Grill-Spector, Rafael Malach
Sep 25, 2009·Journal of Neurophysiology·Steven W Kennerley, Jonathan D Wallis
Sep 26, 2007·Journal of Cognitive Neuroscience·Niklas IhssenAndreas Keil
Mar 6, 2007·Journal of Cognitive Neuroscience·Marco TamiettoBeatrice de Gelder
Jan 28, 2011·Journal of Cognitive Neuroscience·Anna Weinberg, Greg Hajcak
Mar 1, 2012·Journal of Cognitive Neuroscience·Crystal ReeckTobias Egner
May 13, 2010·BMC Neuroscience·Xuebing LiYue-jia Luo
Jun 29, 2012·Biology of Mood & Anxiety Disorders·Francesco AmicoThomas Frodl
Nov 22, 2007·PloS One·Cinzia Di DioGiacomo Rizzolatti
Nov 17, 2012·PloS One·Alessia TessariRoberto Nicoletti
May 7, 2013·PloS One·Antonio SchettinoGilles Pourtois
Sep 27, 2013·PloS One·Flávia Schechtman BelhamMaria Clotilde H Tavares
Nov 6, 2004·Reviews in the Neurosciences·Elizabeth A Kensinger
Dec 22, 2006·Reviews in the Neurosciences·René Hurlemann

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.