PMID: 2492431Jan 16, 1989Paper

Modulation of the Ca2+- or Pb2+-activated K+-selective channels in human red cells. I. Effects of propranolol

Biochimica Et Biophysica Acta
W SchwarzG F Fuhrmann

Abstract

To study the effect of propranolol on the Ca2+- or Pb2+-activated K+ permeability in human erythrocytes, K+ effluxes were compared with single-channel currents. The results demonstrate that propranolol has a twofold effect: (1) it renders the channel protein more sensitive to Ca2+ or Pb2+; and (2) it simultaneously inhibits channel activity and slightly reduces single-channel conductance. The number of active channels is not affected.

References

Jun 24, 1977·The Journal of Membrane Biology·I SzászG Gárdos
Jan 1, 1985·European Biophysics Journal : EBJ·R Grygorczyk, W Schwarz
Mar 1, 1969·Acta Physiologica Scandinavica·A EkmanS Salminen
Feb 16, 1972·Biochemical and Biophysical Research Communications·R M Blum, J F Hoffman
Jan 11, 1984·Biochimica Et Biophysica Acta·G F FuhrmannP A Knauf
Dec 1, 1958·Biochimica Et Biophysica Acta·G GARDOS

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Citations

Jun 1, 1990·The Journal of Membrane Biology·P J RomeroC Melitto
Jan 15, 2014·Brain Research·Manoj ValiyaveettilMadhusoodana P Nambiar
Dec 1, 2003·Environmental Toxicology and Pharmacology·Yasutaka NishizakiYasuo Oyama
May 22, 2003·The International Journal of Biochemistry & Cell Biology·Anthony D Maher, Philip W Kuchel
Sep 1, 1993·Archives Internationales De Physiologie, De Biochimie Et De Biophysique·R E SerraniJ L Corchs
Sep 23, 2003·Environmental Toxicology·Yasutaka NishizakiDavid O Carpenter

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