Modulation of the immune response by Middle East respiratory syndrome coronavirus

Journal of Cellular Physiology
Somayeh ShokriFatemeh Farshadpour

Abstract

Coronavirus (CoV) infections are commonly associated with respiratory and enteric disease in humans and animals. In 2012, a new human disease called Middle East respiratory syndrome (MERS) emerged in the Middle East. MERS was caused by a virus that was originally called human coronavirus-Erasmus Medical Center/2012 but was later renamed as Middle East respiratory syndrome coronavirus (MERS-CoV). MERS-CoV causes high fever, cough, acute respiratory tract infection, and multiorgan dysfunction that may eventually lead to the death of the infected individuals. The exact origin of MERS-CoV remains unknown, but the transmission pattern and evidence from virological studies suggest that dromedary camels are the major reservoir host, from which human infections may sporadically occur through the zoonotic transmission. Human to human transmission also occurs in healthcare facilities and communities. Recent studies on Middle Eastern respiratory continue to highlight the need for further understanding the virus-host interactions that govern disease severity and infection outcome. In this review, we have highlighted the major mechanisms of immune evasion strategies of MERS-CoV. We have demonstrated that M, 4a, 4b proteins and Plppro of MER...Continue Reading

References

Aug 23, 2000·Immunology Today·A Alcami, U H Koszinowski
Nov 20, 2002·Immunogenetics·Mireille T M VossenEmmanuel J H J Wiertz
Apr 15, 2003·Nature Immunology·Katherine A FitzgeraldTom Maniatis
Feb 26, 2004·Nature Medicine·Bart L HaagmansAlbert D M E Osterhaus
Mar 1, 2007·The Journal of Biological Chemistry·Beichu Guo, Genhong Cheng
Mar 31, 2007·The Journal of Biological Chemistry·John Hiscott
Jan 6, 2009·Immunological Reviews·Osamu Takeuchi, Shizuo Akira
Feb 26, 2010·Journal of Virology·Mark A ClementzSusan C Baker
Sep 24, 2010·Future Microbiology·Hye-Ra LeeJae U Jung
Dec 7, 2010·Journal of Structural Biology·Benjamin W NeumanMichael J Buchmeier
Jun 3, 2011·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Lawrence M Pfeffer
Sep 3, 2011·Immunological Reviews·Hiroki KatoTakashi Fujita
Jan 10, 2012·Nature Reviews. Immunology·José M González-NavajasEyal Raz
May 11, 2012·Current Opinion in Virology·Allison L Totura, Ralph S Baric
May 28, 2013·Immunity·Delphine GoubauCaetano Reis e Sousa
Jun 21, 2013·The Lancet Infectious Diseases·Christian DrostenClemens-Martin Wendtner
Jul 26, 2013·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Jasper Fuk-Woo ChanPatrick Chiu-Yat Woo
Aug 14, 2013·Cell Research·Berend Jan BoschBart L Haagmans
Sep 13, 2013·Journal of Virology·Daniela NiemeyerMarcel A Müller
Nov 6, 2013·Annals of Saudi Medicine·Sami Al HajjarKenneth McIntosh
Mar 7, 2014·Proceedings of the National Academy of Sciences of the United States of America·Jincun ZhaoStanley Perlman

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Citations

Oct 2, 2020·Pharmaceuticals·Anastasiia I Petushkova, Andrey A Zamyatnin
Aug 23, 2020·International Journal of Molecular Sciences·Grégorie LebeauPhilippe Gasque
Oct 27, 2020·Frontiers in Immunology·Nima TaefehshokrBryan Heit
Feb 9, 2021·Journal of Ovarian Research·Antonio MacciòClelia Madeddu
Oct 6, 2020·IScience·Johannes BurtscherGrégoire P Millet
Dec 19, 2020·Evolution, Medicine, and Public Health·Bernard Crespi
Dec 17, 2020·Frontiers in Pharmacology·Maria Gracia-HernandezAlejandro Villagra
Oct 29, 2020·Toxicology Reports·Ronald N KostoffAristidis Tsatsakis
Dec 23, 2020·Molecular Therapy : the Journal of the American Society of Gene Therapy·Anna K BlakneyRobin J Shattock
Nov 14, 2020·Medicinal Research Reviews·Yuan Tan, Faqin Tang
Mar 2, 2021·Frontiers in Cellular and Infection Microbiology·Shamila D AlipoorIan M Adcock
Mar 16, 2021·Frontiers in Immunology·Gislane Lelis Vilela de OliveiraCristina Ribeiro de Barros Cardoso
Apr 6, 2021·Oxidative Medicine and Cellular Longevity·Elisabetta FerraroNatalia Malara
Apr 26, 2021·International Immunopharmacology·Seyede Atefe HosseiniReza Kazemi Oskuee
Jul 6, 2021·World Journal of Clinical Cases·Reza TaherkhaniFatemeh Farshadpour
Jul 3, 2021·Cells·Annamaria PaoliniLara Gibellini
Jul 24, 2021·Molecular Biology Reports·K A DvornikovaA Lerner
Jul 13, 2021·Reviews in Medical Virology·Mina Mobini KeshehSomayeh Shokri
Sep 2, 2021·IUBMB Life·Hiu Yan LamKwang Seok Ahn
Sep 23, 2021·Current Microbiology·Pritha BoseShakti P Pattanayak

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