Modulation of the inspiratory-related activity of hypoglossal premotor neurons during ingestion and rejection in the decerebrate cat

Journal of Neurophysiology
T OnoY Nakamura

Abstract

Single-unit activities of the bulbar reticular inspiratory neurons directly projecting to hypoglossal motoneurons were studied during fictive ingestion (e.g., swallowing) and rejection elicited by repetitive stimulation of the superior laryngeal nerve and by application of water to the pharynx in immobilized decerebrated cats. The single-unit activity was recorded during 113 episodes of fictive ingestion from 25 inspiratory neurons directly projecting to hypoglossal motoneurons (single projection neurons) and 7 inspiratory neurons directly projecting to both hypoglossal and phrenic motoneurons (dual projection neurons) in the regions ventrolateral to the nucleus tractus solitarii and dorsomedial to the nucleus ambiguus. All of single projection neurons ceased inspiratory-related rhythmical discharges coincidentally with the onset of repetitive stimulation of the superior laryngeal nerve. The majority of them (19/25, 76%, type A) showed a spike burst during ingestion, whereas the minority (6/25, 24%, type B) kept silent until the end of repetitive stimulation of the superior laryngeal nerve. During fictive ingestion elicited by application of water to the pharynx, the type-A neurons showed a spike burst activity, whereas the typ...Continue Reading

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Citations

Apr 4, 2002·Journal of Neurophysiology·Fabrice RodaArmand Louis Bianchi
May 3, 2006·The Laryngoscope·Roxann Diez GrossMark C Weissler
Apr 30, 2013·Nature·Jeffrey D MooreDavid Kleinfeld
Dec 22, 2015·ELife·Ann L RevillGregory D Funk
Oct 17, 2003·Journal of Neurophysiology·Jean-Charles ViemariGérard Hilaire
Apr 2, 2011·The Journal of Comparative Neurology·Yoichiro SugiyamaYasuo Hisa
Jul 18, 2018·Frontiers in Physiology·Kofi-Kermit HortonChristian Gestreau
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Sep 6, 2008·Journal of Applied Physiology·Denys V VolginLeszek Kubin

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