PMID: 6978472Mar 17, 1982Paper

Modulation of voltage-dependent currents by muscarinic receptor in sympathetic neurones of bullfrog

Neuroscience Letters
T Akasu, K Koketsu

Abstract

The muscarinic actions of acetylcholine (ACh) on the action potentials of bullfrog sympathetic ganglion cells were studied with voltage-clamp experiments. The slow inward current (Isi) carried by Ca2+ was markedly depressed by ACh. ACh also markedly depressed the time-dependent outward current following Isi. The outward current was composed of two components, a TEA-sensitive rectifier K+ current (IK1) and a TEA-insensitive slow rectifier K+ current (IK2). Both of these components were depressed by ACh.

References

Jan 1, 1978·Progress in Neurobiology·K Kuba, K Koketsu
May 1, 1969·The Journal of General Physiology·K Koketsu, S Nishi
Dec 1, 1980·British Journal of Pharmacology·D A Brown, A Constanti
Feb 1, 1960·Journal of Cellular and Comparative Physiology·S NISHI, K KOKETSU

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Citations

Oct 1, 1987·Pflügers Archiv : European journal of physiology·K Tanaka, K Kuba
Nov 1, 1986·Pflügers Archiv : European journal of physiology·U MisgeldH U Dodt
Sep 1, 1991·Brain Research. Brain Research Reviews·R Anwyl
Dec 1, 1986·Journal of the Autonomic Nervous System·S Mochida, H Kobayashi
May 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·Y NakajimaK Yamaguchi
Oct 1, 1988·Trends in Neurosciences·R W TsienA P Fox

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