Mogamulizumab: 2 birds, 1 stone.

Blood
Ryan A Wilcox

Abstract

In this issue of Blood, Duvic et al demonstrate that mogamulizumab, a humanized monoclonal antibody targeting the chemokine receptor CCR4, is well tolerated and has significant clinical activity (overall response rate 36.8%, median duration of response 10.4 months) in heavily pretreated patients with mycosis fungoides (MF) and Sézary syndrome (SS).

References

Oct 9, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ryan A WilcoxLieping Chen
Mar 13, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Michinori OguraRyuzo Ueda
Mar 19, 2014·Blood·Javeed IqbalUNKNOWN Lymphoma Leukemia Molecular Profiling Project and the International Peripheral T-cell Lymphoma Project
Nov 8, 2014·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Xiao NiMadeleine A Duvic
Dec 10, 2014·The Journal of Experimental Medicine·Masao NakagawaLouis M Staudt

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Citations

Feb 6, 2016·Current Opinion in Oncology·Sima Rozati, Youn H Kim
Nov 27, 2015·American Journal of Hematology·Ryan A Wilcox
Mar 1, 2016·American Journal of Clinical Dermatology·Sumana Devata, Ryan A Wilcox
Oct 16, 2016·International Journal of Clinical Oncology·Helen Ma, Maher Abdul-Hay
Dec 7, 2017·Oncoimmunology·Mariona CaboLorenzo Galluzzi
Jul 16, 2019·Expert Opinion on Drug Safety·Salma AfifiFrancine Foss
Jul 19, 2019·IUBMB Life·Carlos Murga-Zamalloa, Ryan A Wilcox
Jul 18, 2019·American Journal of Hematology·Alexandra C HristovRyan A Wilcox
Jan 15, 2020·Der Pathologe·Marion Wobser, Matthias Goebeler
Sep 13, 2019·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·Marion Wobser, Matthias Goebeler
Jun 27, 2017·Expert Opinion on Biological Therapy·Shinichi Makita, Kensei Tobinai
Dec 30, 2016·Journal for Immunotherapy of Cancer·Tycel PhillipsRyan A Wilcox
Jul 15, 2017·Nature Reviews. Drug Discovery·Catherine J HutchingsFiona H Marshall
May 26, 2020·Journal of Hematology & Oncology·Erin Mulvey, Jia Ruan
Jun 11, 2016·Biochemical Society Transactions·Trevor C I Wilkinson
Jan 9, 2018·Leukemia & Lymphoma·Jenna JanigaFarah Abdulla
Jan 2, 2021·Journal of Hematology & Oncology·Katarzyna IżykowskaGrzegorz K Przybylski
Feb 20, 2021·Cancer Gene Therapy·Karan KohliTeresa S Kim
Apr 29, 2021·Seminars in Hematology·John C Reneau, Ryan A Wilcox
Jul 24, 2021·American Journal of Hematology·Alexandra C HristovRyan A Wilcox

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