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MOHCA-seq: RNA 3D models from single multiplexed proximity-mapping experiments

bioRxiv

Apr 25, 2014

Clarence Yu ChengRhiju Das

Abstract

Large RNAs control myriad biological processes but challenge tertiary structure determination. We report that integrating multiplexed •OH cleavage analysis with tabletop deep sequencing (MOHCA-seq) gives nucleotide-resolution proximity maps of RNA structure from single straightforward e...read more

Mentioned in this Paper

Proximal
Ligands
Ligands Activity
Nucleotides
Physiological Processes
RNA
Riboswitch
Deep Sequencing
Multiplex Polymerase Chain Reaction
Three-dimensional
5
19
Paper Details
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MOHCA-seq: RNA 3D models from single multiplexed proximity-mapping experiments

bioRxiv

Apr 25, 2014

Clarence Yu ChengRhiju Das

PMID: 990004556

DOI: 10.1101/004556

Abstract

Large RNAs control myriad biological processes but challenge tertiary structure determination. We report that integrating multiplexed •OH cleavage analysis with tabletop deep sequencing (MOHCA-seq) gives nucleotide-resolution proximity maps of RNA structure from single straightforward e...read more

Mentioned in this Paper

Proximal
Ligands
Ligands Activity
Nucleotides
Physiological Processes
RNA
Riboswitch
Deep Sequencing
Multiplex Polymerase Chain Reaction
Three-dimensional
5
19
Paper Details
References
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  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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