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MOHCA-seq: RNA 3D models from single multiplexed proximity-mapping experiments

bioRxiv

Apr 25, 2014

Clarence Yu ChengRhiju Das

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Abstract

Large RNAs control myriad biological processes but challenge tertiary structure determination. We report that integrating Multiplexed ?OH Cleavage Analysis with tabletop deep sequencing (MOHCA-seq) gives nucleotide-resolution proximity maps of RNA structure from single straightforward e...read more

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  • MOHCA-seq: RNA 3D models from single multiplexed proximity-mapping experiments

    bioRxiv

    Apr 25, 2014

    Clarence Yu ChengRhiju Das

    PMID: 990004556

    DOI: 10.1101/004556

    Abstract

    Large RNAs control myriad biological processes but challenge tertiary structure determination. We report that integrating Multiplexed ?OH Cleavage Analysis with tabletop deep sequencing (MOHCA-seq) gives nucleotide-resolution proximity maps of RNA structure from single straightforward e...read more

    5
    19
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