Molecular analyses of Vibrio cholerae O1 clinical strains, including new nontoxigenic variants isolated in Mexico during the Cholera epidemic years between 1991 and 2000.

Journal of Clinical Microbiology
Marcial Leonardo Lizárraga-Partida, Marie-Laure Quilici


We studied the evolution of Vibrio cholerae O1 during the 1991 to 2000 cholera epidemic in Mexico by biochemical, serological, and molecular characterization of strains collected during this period. Strains were divided into toxigenic and nontoxigenic groups according to the presence or absence of genes encoding cholera toxin. As previously reported, we characterized two populations among toxigenic strains, which were present from the first year of the epidemic. BglI rRNA analysis revealed that these strains had ribotype profiles, denoted M5 and M6 in our study, that were identical to those previously designated Koblavi B5 or Popovic 5 and Popovic 6a or Tamayo B21a, respectively. Ribotype M5 was isolated between 1991 and 1993. This ribotype had a low level of genetic variation as detected by pulsed-field gel electrophoresis (PFGE). Ribotype M6 persisted from 1991 to 2000. However, PFGE profiles suggested that two epidemiologically unrelated strains coexisted within this single ribotype from 1995 until the end of the epidemic. We identified three new BglI ribotypes, Mx1, Mx2, and Mx3, from nontoxigenic V. cholerae O1 strains isolated between 1998 and 2000; one of them grouped strains positive for the toxin-coregulated pilus isla...Continue Reading


Apr 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·U H StroeherP A Manning
Jul 1, 1990·Research in Microbiology·S KoblaviP A Grimont
Jun 1, 1982·Journal of Clinical Microbiology·D J BrennerA G Steigerwalt
Jan 1, 1995·Journal of Clinical Microbiology·A CoelhoC A Salles
Mar 1, 1993·The Journal of Infectious Diseases·I K WachsmuthP A Blake
Sep 1, 1993·Journal of Clinical Microbiology·T PopovicK Wachsmuth
Jul 1, 1995·The Journal of Infectious Diseases·G M EvinsR V Tauxe
Jul 1, 1994·Journal of Clinical Microbiology·D N CameronT J Barrett
May 1, 1997·Journal of Clinical Microbiology·A DalsgaardD N Taylor
Jul 1, 1997·Journal of Medical Microbiology·M TamayoP A Grimont
Jan 28, 1999·Research in Microbiology·M DamianP A Grimont
Feb 13, 1999·Journal of Clinical Microbiology·P BeltránA Cravioto
Aug 3, 2000·International Journal of Epidemiology·R J Borroto, R Martinez-Piedra
May 26, 2001·Applied and Environmental Microbiology·I N RiveraR R Colwell
May 7, 2002·Journal of Medical Microbiology·M PourshafieP A D Grimont
Jan 9, 2003·Journal of Clinical Microbiology·Mariana PichelNorma Binsztein
Feb 10, 2004·Proceedings of the National Academy of Sciences of the United States of America·Shah M FaruqueJohn J Mekalanos
Dec 6, 2005·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Jaime SepúlvedaLourdes García-García

❮ Previous
Next ❯


Apr 21, 2012·Journal of Clinical Microbiology·Munirul AlamAlejandro Cravioto
Dec 18, 2010·Future Microbiology·Tushar Suvra BhowmickB L Sarkar
Feb 24, 2016·Frontiers in Microbiology·Goutam ChowdhuryThandavarayan Ramamurthy
Feb 5, 2015·International Journal of Environmental Health Research·Abraham GuerreroMarcial Leonardo Lizárraga-Partida
Nov 15, 2019·Journal of Food Protection·Claudia VillicañaJosefina León-Félix
Nov 11, 2017·Science·Daryl DommanNicholas R Thomson
Aug 10, 2019·Frontiers in Public Health·Thandavarayan RamamurthyGopinath Balakrish Nair

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved