Molecular analysis of infant acute leukemia

Leukemia & Lymphoma
Joanne M HildenJ H Kersey

Abstract

Infant acute leukemia, known to have a poor outcome with conventional therapy, usually has a molecular rearrangement at chromosome band 11q23. The 11q23 translocation partner is typically at 4q21 in infant ALL, but other 11q23 translocation partners occur in infant ALL and AML. The MLL gene at 11q23, and the AF4 gene at 4q21, have been extensively studied to identify heterogeneity of structural rearrangement and prognostic indicators, to look for clues as to etiology, and to improve therapy.

References

Dec 11, 1991·Proceedings of the National Academy of Sciences of the United States of America·S Ziemin-van der PoelJ D Rowley
Mar 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·A M MazoI B Dawid
Sep 1, 1990·The Biochemical Journal·D S Latchman
Nov 1, 1985·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G ReamanD Hammond
Aug 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·P H DomerS J Korsmeyer
May 23, 1995·Proceedings of the National Academy of Sciences of the United States of America·R BaffaC M Croce
Dec 6, 1994·Proceedings of the National Academy of Sciences of the United States of America·M J ThirmanJ D Rowley
Aug 16, 1994·Proceedings of the National Academy of Sciences of the United States of America·R PrasadE Canaani
May 1, 1994·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C H PuiW L Furman
Jul 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·Q MaA M Buchberg
May 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·T NakamuraP C Nowell
Mar 29, 1996·Science·A ShilatifardJ W Conaway
Jan 1, 1996·Genetic Analysis : Biomolecular Engineering·J L FrestedtJ H Kersey
May 1, 1996·Journal of Pediatric Hematology/oncology·T G GrossE M MacMahon

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Citations

May 10, 2001·Proceedings of the National Academy of Sciences of the United States of America·T MercherO A Bernard
Jun 14, 2003·Leukemia & Lymphoma·Eiichi IshiiMariko Eguchi
Oct 20, 2009·Seminars in Oncology·Karen AlbrittonArchie Bleyer
Apr 20, 2000·Journal of the National Cancer Institute·F P Perera

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