journal cover

Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease

Neurobiology of Aging

Jul 1, 1997

S WebsterJ Rogers

PMID: 9330973

Abstract

The membrane attack complex, C5b-9, is of considerable importance in many inflammatory reactions. It is the terminal, cytolytic component of both classical and alternative pathway activation, and its presence presupposes other potentially destructive complement constituents, including a...read more

Mentioned in this Paper

Complement Membrane Attack Complex
Buffers
Familial Alzheimer Disease (FAD)
Biochemical Pathway
Alb
Cortex Bone Disorders
Tissue Membrane
Adrenal Cortex Diseases
Immunohistochemistry
Immunoreactivity
59
Paper Details
References
  • References19
  • Citations109
12
  • References19
  • Citations109
12345...

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Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Complement activation by beta-amyloid in Alzheimer disease

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Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease

Neurobiology of Aging

Jul 1, 1997

S WebsterJ Rogers

PMID: 9330973

DOI:

Abstract

The membrane attack complex, C5b-9, is of considerable importance in many inflammatory reactions. It is the terminal, cytolytic component of both classical and alternative pathway activation, and its presence presupposes other potentially destructive complement constituents, including a...read more

Mentioned in this Paper

Complement Membrane Attack Complex
Buffers
Familial Alzheimer Disease (FAD)
Biochemical Pathway
Alb
Cortex Bone Disorders
Tissue Membrane
Adrenal Cortex Diseases
Immunohistochemistry
Immunoreactivity
59

Similar Papers Found In These Feeds

Alternative Complement Pathway

The Alternative Complement Pathway is part of the innate immune system, and activation generates membrane attack complexes that kill pathogenic cells. Discover the latest research on the Alternative Complement Pathway.

Antibodies: Complement Activation

The complement system can be activated by antigen-associated antibody. In the classical pathway of complement activation, C1q, C4b, and C3b are all able to bind to the Fc portion of IgG or IgM. Find the latest research on antibodies and complement activation here.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Complement activation by beta-amyloid in Alzheimer disease

Proceedings of the National Academy of Sciences of the United States of AmericaNovember 1, 1992
J RogersP Ward
Neuroscience Letters

Activation of the classical complement pathway in brain tissue of Alzheimer patients

Neuroscience LettersDecember 15, 1989
Patrick L McGeerEdith G McGeer
Paper Details
References
  • References19
  • Citations109
12
  • References19
  • Citations109
12345...
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