PMID: 3773886Aug 1, 1986Paper

Molecular and functional diversity of non-histone protein fraction NHCP1 from hamster Kirkman-Robbins hepatoma and liver

Molecular and Cellular Biochemistry
Z M KiliańskaL Kłyszejko-Stefanowicz

Abstract

Non-histone protein fraction NHCP1 of micrococcal nuclease-sensitive and nuclease-resistant chromatin from Kirkman-Robbins hepatoma and hamster liver was studied by two-dimensional electrophoresis followed by Coomassie and silver staining and by microcomplement fixation technique in the presence of antibodies elicited against NHCP1 of both tissues. Apart from many common spots several tissue specific components associated with either nuclease-sensitive or nuclease-resistant chromatin were found. The presence of tissue specific components among NHCP1 from hepatoma and liver was confirmed by immunological analysis. It was stated that these components are exclusively localized in nuclease-resistant part of chromatin from neoplastic and normal tissues thus suggesting their structural function.

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Citations

Jan 18, 1990·Molecular and Cellular Biochemistry·Z WojtkowiakL Kłyszejko-Stefanowicz
Jan 1, 1989·The International Journal of Biochemistry·Z KilianskaL Klyszejko-Stefanowicz
Sep 1, 1992·The International Journal of Biochemistry·A Lipińska, M Gaczyński
Dec 1, 1991·Journal of Toxicology and Environmental Health·J T ZelikoffR B Schlesinger

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