Abstract
Correct balance between bacterial RNA degradation and synthesis is essential for controlling expression level of all RNAs. The RNA polymerase, which performs the RNA synthesis, is highly conserved across the bacterial domain. However, this is surprisingly not the case for the RNA degradation machinery, which is composed of different subunits and performs different enzymatic reactions, depending on the organism. In Escherichia coli, the RNA decay is performed by the degradosome complex, which forms around the membrane-associated endoribonuclease RNase E, and is stable enough to be purified without falling apart. In contrast, many Firmicutes, for example, Bacillus subtilis, Staphylococcus aureus, and Streptococcus pneumoniae, do not encode an RNase E homolog, but instead have the endoribonuclease RNase Y and the exo- and endo-ribonuclease RNase J complex. A wide range of experiments have been performed, mainly with B. subtilis and S. aureus, to determine which interactions exist between the various RNA decay enzymes in the Firmicutes, with the goal of understanding how RNA degradation (and thus gene expression homeostasis and regulation) is organized in these organisms. The in vivo and in vitro data is diverse, and does not alway...Continue Reading
References
May 9, 1996·Nature·B PyA J Carpousis
Aug 6, 1996·Proceedings of the National Academy of Sciences of the United States of America·D J SenGuptaM Wickens
May 20, 1998·Proceedings of the National Academy of Sciences of the United States of America·G KarimovaD Ladant
Sep 10, 1998·Genes & Development·N F VanzoA J Carpousis
Jul 9, 2004·Journal of Molecular Biology·Anastasia J CallaghanBen F Luisi
Nov 4, 2004·Molecular Microbiology·Teppei MoritaHiroji Aiba
Apr 16, 2005·Nucleic Acids Research·Sergine EvenHarald Putzer
Sep 29, 2006·Microbiology·Alison HuntJeff Errington
Jan 19, 2007·Molecular Microbiology·Robert A BrittonCiarán Condon
Jan 22, 2008·Nature Structural & Molecular Biology·Inés Li de la Sierra-GallayHarald Putzer
Feb 6, 2009·Molecular & Cellular Proteomics : MCP·Fabian M CommichauJörg Stülke
Sep 26, 2009·The EMBO Journal·Karen ShahbabianHarald Putzer
Dec 23, 2009·Molecular Microbiology·Julia V Bugrysheva, June R Scott
Dec 23, 2009·Molecular Microbiology·Nathalie MathyCiarán Condon
Jun 25, 2010·Molecular Microbiology·Martin Lehnik-HabrinkJörg Stülke
Jun 29, 2011·Proteomics·Olivier DelumeauPhilippe Noirot
Jul 19, 2011·Journal of Bacteriology·Christelle M RouxPaul M Dunman
Aug 2, 2011·Journal of Bacteriology·Martin Lehnik-HabrinkJörg Stülke
Sep 7, 2011·Structure·Joseph A NewmanRichard J Lewis
Dec 27, 2011·Journal of Molecular Biology·Joseph A NewmanRichard J Lewis
Mar 27, 2012·Applied and Environmental Microbiology·Peter Redder, Patrick Linder
Jul 12, 2012·Molecular Microbiology·Gabriella MarincolaChristiane Wolz
Nov 24, 2012·Journal of Bacteriology·Martin Lehnik-HabrinkJörg Stülke
Mar 19, 2013·Journal of Bacteriology·Sabine FigaroCiarán Condon
Nov 5, 2013·Journal of Bacteriology·Ailar JamalliHarald Putzer
Mar 4, 2014·PLoS Genetics·Patrick LinderPeter Redder
Aug 6, 2014·Journal of Bacteriology·Andrew N KellerPeter J Lewis
Apr 25, 2015·FEMS Microbiology Reviews·Peter RedderPatrick Linder
May 3, 2015·FEMS Microbiology Reviews·Sylvain DurandPascale Romby
May 6, 2015·Nucleic Acids Research·Ye ZhaoYuejin Hua
May 23, 2015·RNA Biology·Caroline GiraudPatrick Linder
Jun 23, 2015·Molecular Microbiology·Soraya Aït-Bara, Agamemnon J Carpousis
Aug 9, 2015·Nucleic Acids Research·Xue-Yuan PeiBen F Luisi
Sep 12, 2015·The Journal of Biological Chemistry·Elizabeth A HoffmanDavid T Auble
Oct 17, 2015·PLoS Genetics·Vanessa KhemiciPeter Redder
Jan 23, 2016·The Journal of Biological Chemistry·Elizabeth SalvoDavid H Bechhofer
Jan 26, 2016·Current Opinion in Microbiology·Vanessa Khemici, Patrick Linder
Jul 28, 2016·RNA Biology·Matthias Gimpel, Sabine Brantl
Oct 7, 2016·Frontiers in Microbiology·Nora Cascante-EstepaJörg Stülke
Mar 10, 2017·RNA Biology·Stéphane HausmannPeter Redder
Citations
Sep 14, 2019·BioFactors·Wenbo ZhaoJinhao Sun
Feb 8, 2020·Nucleic Acids Research·Duy Khanh PhungBéatrice Clouet-d'Orval
May 19, 2019·Annual Review of Virology·T Dendooven, R Lavigne
Oct 18, 2019·Frontiers in Microbiology·Rong MuJustin Merritt
Feb 20, 2020·MBio·Lina HamoucheHarald Putzer
Apr 4, 2019·ELife·Lucy Chou-Zheng, Asma Hatoum-Aslan
Apr 1, 2021·Nucleic Acids Research·Soumaya LaalamiHarald Putzer
Nov 5, 2019·Trends in Biochemical Sciences·Alejandro Tejada-ArranzHilde de Reuse
Jun 3, 2021·Microorganisms·Inam Ul Haq, Sabine Brantl
Jun 23, 2021·Nucleic Acids Research·Martin BendaJörg Stülke
Aug 28, 2021·Frontiers in Microbiology·Brice Felden, Yoann Augagneur