Molecular Approaches for Diagnosis, Therapy and Prevention of Cow´s Milk Allergy

Nutrients
B LinhartRudolf Valenta

Abstract

Cow´s milk is one of the most important and basic nutrients introduced early in life in our diet but can induce IgE-associated allergy. IgE-associated allergy to cow´s milk can cause severe allergic manifestations in the gut, skin and even in the respiratory tract and may lead to life-threatening anaphylactic shock due to the stability of certain cow´s milk allergens. Here, we provide an overview about the allergen molecules in cow´s milk and the advantages of the molecular diagnosis of IgE sensitization to cow´s milk by serology. In addition, we review current strategies for prevention and treatment of cow´s milk allergy and discuss how they could be improved in the future by innovative molecular approaches that are based on defined recombinant allergens, recombinant hypoallergenic allergen derivatives and synthetic peptides.

References

Dec 1, 1995·The Journal of Allergy and Clinical Immunology·S SpitzauerH Rumpold
Dec 22, 1998·Allergy·J M Wal
Jun 26, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P RestaniC L Galli
Aug 24, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·I SéloJ Wal
Aug 24, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A UmpiérrezJ Sastre
Feb 12, 2000·The Journal of Allergy and Clinical Immunology·B PandjaitanS Spitzauer
Nov 9, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·R SporikC S Hosking
Mar 22, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K M SaarinenE Savilahti
Dec 1, 2001·International Archives of Allergy and Immunology·K M JärvinenH A Sampson
Sep 26, 2002·Clinical and Experimental Immunology·P RozenfeldC A Fossati
Dec 19, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Alberto MartelliAlessandro Fiocchi
Dec 6, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·R ReiningerS Spitzauer
Nov 13, 2004·The Journal of Allergy and Clinical Immunology·Tamara T PerryRobert A Wood
Nov 26, 2004·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jean-Michel Wal
Sep 17, 2005·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A VerstegeB Niggemann
Mar 2, 2006·Journal of Immunological Methods·Justus AdédoyinMarianne van Hage
Mar 6, 2007·The Journal of Allergy and Clinical Immunology·Justus AdédoyinMarianne van Hage
May 4, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ines SwobodaSusanne Spitzauer
Aug 8, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·J Vicente-SerranoI Moneo
Oct 9, 2007·Gastroenterology·Glenn T FurutaUNKNOWN First International Gastrointestinal Eosinophil Research Symposium (FIGERS) Subcommittees
Nov 1, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·U SchulmeisterS Spitzauer
Nov 16, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Mauro CalvaniZicari Anna Maria
Dec 26, 2007·The Journal of Allergy and Clinical Immunology·Giorgio LongoAlessandro Ventura
Feb 14, 2008·The Journal of Allergy and Clinical Immunology·Raffaela CampanaRudolf Valenta
Jun 10, 2008·The Journal of Allergy and Clinical Immunology·Andrea von BergUNKNOWN GINIplus study group
Sep 9, 2008·The Journal of Allergy and Clinical Immunology·Inmaculada CerecedoHugh A Sampson
Oct 28, 2008·The Journal of Allergy and Clinical Immunology·Justin M SkripakRobert A Wood
Apr 14, 2009·The Journal of Allergy and Clinical Immunology·Hans GrönlundMarianne van Hage
May 21, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ulrike SchulmeisterSusanne Spitzauer
Dec 17, 2009·Current Medical Research and Opinion·Hania Szajewska, Andrea Horvath
Mar 11, 2010·Journal of Pediatric Gastroenterology and Nutrition·Dominik D Alexander, Michael D Cabana
May 11, 2010·The Journal of Allergy and Clinical Immunology·Christophe DupontPierre-Henri Benhamou
May 11, 2010·The Journal of Allergy and Clinical Immunology·S Allan Bock
May 14, 2010·The Journal of Allergy and Clinical Immunology·Emma M SavilahtiHugh A Sampson
May 15, 2010·The Journal of Allergy and Clinical Immunology·Heidrun HochwallnerSusanne Spitzauer
Jul 17, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L E D'UrbanoG Cavagni
Sep 24, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H HochwallnerS Spitzauer
Nov 9, 2010·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Giovanni Battista PajnoGiovanni Passalacqua
Apr 2, 2011·Pediatric Clinics of North America·Jacob D KattanKirsi M Järvinen
Apr 13, 2011·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A MartorellR Félix
May 7, 2011·The Journal of Allergy and Clinical Immunology·Kari C NadeauDale T Umetsu
Jul 5, 2011·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Joanne Walsh, Norma O'Flynn
Dec 2, 2011·The Journal of Allergy and Clinical Immunology·Corinne A KeetRobert A Wood

❮ Previous
Next ❯

Citations

Dec 22, 2019·Sensors·Monika NehraGiovanna Marrazza
Aug 23, 2019·Nutrients·R J Joost van Neerven, Huub F J Savelkoul
Nov 24, 2020·Frontiers in Immunology·Ann-Marie Malby SchoosWillem van de Veen
Mar 9, 2021·Frontiers in Immunology·Huey-Jy HuangRudolf Valenta
May 8, 2021·The Journal of Allergy and Clinical Immunology. in Practice·Peter KopačPeter Korošec
Jun 8, 2021·Frontiers in Physiology·Lindsay Sawyer
Jul 3, 2021·Children·Aikaterini Anagnostou

❮ Previous
Next ❯

Methods Mentioned

BETA
chips
gene knockout

Clinical Trials Mentioned

NCT02223182

Software Mentioned

MeDALL
EuroPrevall

Related Concepts

Related Feeds

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

Methods : a Companion to Methods in Enzymology
S VrtalaRudolf Valenta
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
Mirela CurinRudolf Valenta
Deutsche medizinische Wochenschrift
R HOIGNE, H P BIEDERMANN
Medizinische Monatsschrift für Pharmazeuten
N C PauschG Reiss
© 2022 Meta ULC. All rights reserved