PMID: 7371638Mar 1, 1980Paper

Molecular architecture of annelid erythrocruorins. Extracellular hemoglobin of Arenicola marina (Polychaeta)

European Journal of Biochemistry
J M Pionetti, J Pouyet

Abstract

The respiratory protein, erythrocruorin, of the annelid Arenicola marina was investigated. Spectral properties show many analogies with those of vertebrate hemoglobine. 144 heme groups (ferroprotoporphyrin) were found in the whole molecule, which has a relative molecular mass of 3.56 X 10(6), as determined by sedimentation equilibrium, and an isoelectric point of 4.69. Protein dissociation patterns were analysed by electrophoresis after denaturation in the presence of dodecylsulfate, with and without 2-mercaptoethanol. A tentative model associating molecular mass of the native molecule, heme content, molecular mass of the polypeptide chains and functional properties is proposed. A twelfth subunit of A. marina erythrocruorin would contain twelve heme groups arranged in three functional units made up of four protomers, half of these being covalently bound to non-heme chains; two structural chains would be spatially arranged as bonds between the subunits.

References

Jan 1, 1977·Annual Review of Biophysics and Bioengineering·E Antonini, E Chiancone
Mar 1, 1976·The Biochemical Journal·E J WoodM S Robinson
Oct 1, 1973·Comparative Biochemistry and Physiology. A, Comparative Physiology·R M Wells
Oct 24, 1968·Analytical Biochemistry·J Margolis, K G Kenrick
May 1, 1971·Analytical Biochemistry·A D FriesenF E Ashton
Nov 1, 1970·Archives of Biochemistry and Biophysics·M R Rossi FanelliE Antonini
Mar 1, 1964·Biochemistry·D A YPHANTIS
Jun 17, 1960·Biochimica Et Biophysica Acta·J ROCHEJ P THIERY

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Citations

Jul 19, 2014·Journal of Biotechnology·Tony Le GallTristan Montier
Oct 19, 2006·Biophysical Chemistry·Jose A C BispoCarlos F S Bonafe
Jun 29, 2005·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Jose Ailton Conceicao BispoCarlos Francisco Sampaio Bonafe
Jun 1, 1981·Journal of Muscle Research and Cell Motility·C GerdayN Gerardin-Otthiers
Jun 1, 1981·Biochimie·S Rodriguez-Bravo, J M Pionetti

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